Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.39 |
| ▸ | KDM5A | P29375 | 3/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28617731 | 1.00 | S1PR2 (0.41) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL10802683 | 0.80 | DNM1 (0.40) | DNM1CES2CES1KDM5APHF8 | |
| SCHEMBL13278947 | 0.80 | GPR84 (0.44) | DNM1CES2CES1PPARGPPARD | |
| SCHEMBL31079557 | 0.80 | DNM1 (0.42) | DNM1CES2CES1PPARGPPARD | |
| SCHEMBL28849335 | 0.80 | DNM1 (0.42) | DNM1CES2CES1PPARGPPARD | |
| SCHEMBL10878603 | 0.80 | GPR84 (0.44) | DNM1CES2CES1PPARGPPARD | |
| SCHEMBL5361611 | 0.80 | GPR84 (0.44) | DNM1CES2CES1PPARGPPARD | |
| SCHEMBL18641846 | 0.80 | DNM1 (0.42) | DNM1CES2CES1PPARGPPARD | |
| SCHEMBL31079440 | 0.80 | DNM1 (0.42) | DNM1CES2CES1PPARGPPARD | |
| SCHEMBL29112735 | 0.80 | DNM1 (0.42) | DNM1CES2CES1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963472-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOSITIONS | RECKITT BENCKISER UK LTD (GB) | 2011-07-20 | — | — | EP | disclosed |