Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12460067 | 0.87 | ALDH1A1 (0.45) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL14208887 | 0.87 | ALDH1A1 (0.45) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL10247277 | 0.83 | ALDH1A1 (0.48) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL9987332 | 0.83 | L3MBTL1 (0.47) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL12460943 | 0.83 | ALDH1A1 (0.48) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL23059656 | 0.83 | HDAC2 (0.51) | HSD11B1HDAC2HDAC1RARBMEN1 | |
| SCHEMBL19269342 | 0.80 | ALDH1A1 (0.52) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL23308385 | 0.80 | ALDH1A1 (0.52) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL24255835 | 0.80 | ALDH1A1 (0.52) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL14079818 | 0.80 | ALDH1A1 (0.52) | MEN1ALDH1A1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9496504-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-15 | — | — | US | disclosed |
| US-9496504-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-15 | — | — | US | disclosed |
| US-20120305851-A1 | Materials for Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2012-12-06 | — | — | US | disclosed |
| US-20120305851-A1 | Materials for Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2012-12-06 | — | — | US | disclosed |
| WO-2011085781-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120305851-A1 | Materials for Organic Electroluminescent Devices | L1CAM, EFNA1, EPCAM | HSD11B1 1551/4885HDAC2 3972/4885HDAC1 3387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.