Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714334 | 0.87 | HRH3 (0.43) | HRH3USP30ARPTGDR2NR3C1 | |
| SCHEMBL13184921 | 0.85 | HRH3 (0.45) | HRH3ARSLC6A9GPR119CYP11B1 | |
| SCHEMBL3125585 | 0.85 | HRH3 (0.42) | HRH3USP30ARPTGDR2NR3C1 | |
| SCHEMBL3121798 | 0.85 | HRH3 (0.42) | HRH3USP30ARPTGDR2NR3C1 | |
| SCHEMBL1619495 | 0.83 | PTGDR2 (0.44) | HRH3USP30ARPTGDR2ICMT | |
| SCHEMBL9969445 | 0.83 | SLC6A9 (0.47) | HRH3USP30ARPTGDR2ICMT | |
| SCHEMBL5314540 | 0.83 | HRH3 (0.40) | HRH3USP30ARPTGDR2ICMT | |
| SCHEMBL3119850 | 0.83 | HRH3 (0.40) | HRH3USP30ARPTGDR2NR3C1 | |
| SCHEMBL15924404 | 0.83 | ALDH1A1 (0.50) | HRH3 | |
| SCHEMBL17654321 | 0.83 | ALDH1A1 (0.50) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481966-B1 | NOVEL ARYLAMIDINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2011-07-20 | — | — | EP | disclosed |