SCHEMBL12461

SCHEMBL12461

Cc1ccc2c(c1)CCN2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.59
DRD4 P21917 1/20 0.59
PARP10 Q53GL7 3/20 0.56
PARP11 Q9NR21 2/20 0.56
PARP1 P09874 1/20 0.52
MAPT P10636 3/20 0.44
ALDH1A1 P00352 3/20 0.44
GAA P10253 2/20 0.44
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 2/20 0.41
ALOX15 P16050 2/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
THRB P10828 1/20 0.41
CASP1 P29466 1/20 0.41
HTT P42858 1/20 0.41
CASP7 P55210 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HTR5A P47898 1/20 0.41
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL531817 0.88 MAPT (0.54) DRD2DRD4PARP10PARP11PARP1
SCHEMBL4868930 0.86 MAPT (0.49) DRD2DRD4PARP10PARP11PARP1
SCHEMBL21707873 0.84 MAPT (0.47) DRD2DRD4PARP10PARP11PARP1
SCHEMBL19969998 0.84 DRD2 (0.52) DRD2DRD4PARP10PARP11PARP1
SCHEMBL426519 0.83 PARP10 (0.56) DRD2DRD4PARP10PARP11PARP1
SCHEMBL30564582 0.83 PARP10 (0.56) DRD2DRD4PARP10PARP11PARP1
Hydrochloric Acid SCHEMBL549603 0.81 PARP10 (0.55) DRD2DRD4PARP10PARP11PARP1
SCHEMBL14619655 0.80 DRD2 (0.47) DRD2DRD4PARP10PARP11PARP1
SCHEMBL31504071 0.80 PARP10 (0.64) DRD2DRD4PARP10PARP11MAPT
SCHEMBL31504072 0.79 DRD2 (0.50) DRD2DRD4PARP10PARP11PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 687 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117229275-B Novel 2-acetamido thiazole compound and preparation method and application thereof 北京中医药大学 2024-06-18 CN claimed
WO-2024115863-A1 FUEL COMPOSITION COMPRISING A RENEWABLE BASE AND A NITROGEN-CONTAINING HETEROCYCLIC AROMATIC COMPOUND TOTALENERGIES ONETECH (FR) 2024-06-06 WO claimed
CN-115353478-A Preparation method of indole compound 南京工业大学 2022-11-18 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-7186734-B2 Aryl imidazoles and related compounds as C5a receptor modulators NEUROGEN CORPORATION (US) 2007-03-06 US claimed
EP-1490343-A1 NEW ARYL IMIDAZOLES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS Neurogen Corporation (US) 2004-12-29 EP claimed
US-20040116424-A1 Aryl imidazoles and related compounds as C5a receptor modulators NEUROGEN CORPORATION 2004-06-17 US claimed
WO-2003082829-A1 NEW ARYL IMIDAZOLES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS NEUROGEN CORPORATION (US) 2003-10-09 WO claimed
EP-0976731-B1 PROCESS FOR PRODUCING 5-METHYLINDOLINES IHARA CHEMICAL IND CO (JP) 2002-09-25 EP claimed
US-6066744-A Process for producing 5-methylindolines IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2000-05-23 US claimed
EP-0976731-A1 PROCESS FOR PRODUCING 5-METHYLINDOLINES Ihara Chemical Industry Co., Ltd. (JP) 2000-02-02 EP claimed
JP-10279557-A None JP disclosed
CN-116145156-B Indoline compound preparation method based on organic electronic synthesis 六盘水师范学院 2026-05-15 CN disclosed
EP-4692071-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS TOKUYAMA CORPORATION (JP) 2026-02-11 EP disclosed
US-20250171420-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME MONTE ROSA THERAPEUTICS AG (CH) 2025-05-29 US disclosed
US-4723007-A ANALGESICS, ANTIPSYCHOTIC AGENTS; INTERMEDIATES FOR PROCESSING HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1988-02-02 US disclosed
US-4663453-A Benzo[b]pyrrolo[3,2,1-jk][1,4]benzodiazepines having dopamine receptor activity HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1987-05-05 US disclosed
US-4617313-A ANTIDEPRESSANTS SYNTHELABO (FR) 1986-10-14 US disclosed
EP-0129692-A2 Dibenzodiazepin derivatives, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1985-01-02 EP disclosed
US-4159271-A CYCLIZATION OF A 2-HALOGENOPHENETHYLAMINE IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1979-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171420-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME PSMA1, CSNK1G1, CSNK1A1 DRD2 4529/4885DRD4 4727/4885PARP10 705/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR DRD2 4401/4885DRD4 2097/4885PARP10 4841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.