Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
| ▸ | GSK3A | P49840 | 1/20 | 0.58 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.58 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.58 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8240613 | 0.86 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL13922914 | 0.86 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL1431669 | 0.85 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL22281368 | 0.85 | POLB (0.59) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL12062262 | 0.85 | ALDH1A1 (0.60) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL5197796 | 0.85 | MAPT (0.60) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL30440556 | 0.85 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL13922820 | 0.83 | RAB9A (0.64) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL19116541 | 0.82 | SMN1; SMN2 (0.56) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL8434070 | 0.82 | RAB9A (0.67) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697312-B1 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA AS (DK) | 2011-07-20 | — | — | EP | disclosed |