SCHEMBL12463049

SCHEMBL12463049

CCCC(C)(C)C(=O)Nc1cccc2c(NC(=O)C(C)(C)CCC)cccc12

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ POLB P06746 2/20 0.50
▸ LMNA P02545 1/20 0.50
▸ EPHX1 P07099 1/20 0.44
▸ ALDH1A1 P00352 4/20 0.44
▸ MMP8 P22894 1/20 0.44
▸ GAA P10253 2/20 0.43
▸ HPGD P15428 1/20 0.42
▸ MAPK1 P28482 1/20 0.39
▸ CETP P11597 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ EP300 Q09472 1/20 0.38
▸ HDAC1 Q13547 1/20 0.38
▸ HDAC7 Q8WUI4 1/20 0.38
▸ HDAC8 Q9BY41 1/20 0.38
▸ HDAC6 Q9UBN7 1/20 0.38
▸ RIPK1 Q13546 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16300542 0.81 POLB (0.58) MEN1KMT2APOLBLMNAALDH1A1
SCHEMBL28592279 0.80 MEN1 (0.50) MEN1KMT2ATDP1POLBLMNA
SCHEMBL10064143 0.80 LMNA (0.57) MEN1KMT2ATDP1POLBLMNA
SCHEMBL16256513 0.78 POLB (0.56) MEN1KMT2APOLBLMNAALDH1A1
SCHEMBL10684049 0.78 PDK1 (0.59) MEN1KMT2ATDP1POLBLMNA
SCHEMBL12284944 0.78 CETP (0.59) MEN1KMT2APOLBLMNAALDH1A1
SCHEMBL11867606 0.78 MEN1 (0.64) MEN1KMT2ATDP1POLBLMNA
SCHEMBL12863541 0.78 POLB (0.58) MEN1KMT2APOLBLMNAEPHX1
SCHEMBL7440675 0.76 MEN1 (0.71) MEN1KMT2ATDP1ALDH1A1MMP8
SCHEMBL14389906 0.75 MEN1 (0.46) MEN1KMT2ATDP1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7985535-B2 Image-forming method and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-07-26 — — US disclosed
US-20110020751-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRODUCTION PROCESS OF LITHOGRAPHIC PRINTING PLATE USING THE PRECURSOR FUJIFILM CORPORATION (JP) 2011-01-27 — — US disclosed
US-20090181173-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-07-16 — — US disclosed
US-20090148792-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-06-11 — — US disclosed
US-20090087781-A1 IMAGE-FORMING METHOD AND LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-04-02 — — US disclosed
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