Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18467799 | 0.80 | KDM4E (0.41) | KDM4EL3MBTL1FFAR1FFAR4HRH3 | |
| SCHEMBL9494958 | 0.79 | ACACB (0.49) | FFAR1FFAR4ACACBCYP2A6 | |
| SCHEMBL18479364 | 0.78 | KDM4E (0.41) | KDM4EL3MBTL1FFAR1FFAR4HRH3 | |
| SCHEMBL20448721 | 0.76 | KDM4E (0.42) | KDM4EL3MBTL1FFAR1FFAR4HRH3 | |
| SCHEMBL10162239 | 0.76 | L3MBTL1 (0.42) | KDM4EL3MBTL1FFAR1FFAR4HRH3 | |
| SCHEMBL2760434 | 0.76 | CYP2A6 (0.48) | KDM4EL3MBTL1HRH3NPC1RAB9A | |
| SCHEMBL23870296 | 0.75 | KCNH2 (0.38) | KDM4EL3MBTL1FFAR1FFAR4ACACB | |
| SCHEMBL10727406 | 0.74 | CYP2A6 (0.56) | FFAR1FFAR4ACACBCYP2A6 | |
| SCHEMBL9498001 | 0.74 | ACACB (0.48) | FFAR1FFAR4ACACB | |
| SCHEMBL10140986 | 0.74 | CCR1 (0.44) | RAB9ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011081918-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC (US) | 2011-07-07 | — | — | WO | disclosed |