SCHEMBL12464256

SCHEMBL12464256

C=C(N=C1C=CC(=NOC(=O)c2ccccc2)C=C1)C(=O)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
MEN1 O00255 1/20 0.40
MAPK1 P28482 1/20 0.40
PLA2G7 Q13093 2/20 0.40
MAPT P10636 5/20 0.39
ALDH1A1 P00352 5/20 0.38
F2 P00734 2/20 0.38
LMNA P02545 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 2/20 0.37
ATM Q13315 1/20 0.37
PLA2G1B P04054 1/20 0.37
ATG4B Q9Y4P1 1/20 0.37
CES2 O00748 2/20 0.37
CES1 P23141 2/20 0.37
CYP2C9 P11712 1/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2610235 0.84 F2 (0.52) KMT2AMEN1MAPK1PLA2G7MAPT
SCHEMBL20169649 0.78 KMT2A (0.47) KMT2AMEN1MAPK1PLA2G7MAPT
SCHEMBL7638875 0.78 PLA2G7 (0.46) KMT2AMEN1MAPK1PLA2G7MAPT
SCHEMBL14390482 0.76 PLA2G7 (0.45) KMT2AMEN1MAPK1PLA2G7MAPT
SCHEMBL6436150 0.75 PLA2G7 (0.44) KMT2AMEN1MAPK1PLA2G7MAPT
SCHEMBL21261970 0.70 KMT2A (0.46) KMT2AMEN1MAPK1MAPTALDH1A1
SCHEMBL20060477 0.69
SCHEMBL18221803 0.69 GAA (0.59) KMT2AMEN1MAPK1MAPTALDH1A1
SCHEMBL18221811 0.67 NPC1 (0.58) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL1348555 0.67 NPC1 (0.54) KMT2APLA2G7MAPTALDH1A1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1722272-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2011-07-06 EP disclosed