SCHEMBL7638875

SCHEMBL7638875

O=C1C=CC(=NOC(=O)c2ccccc2)C=C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 3/20 0.46
KMT2A Q03164 6/20 0.46
ALDH1A1 P00352 3/20 0.46
F2 P00734 2/20 0.46
HPGD P15428 2/20 0.46
ATM Q13315 1/20 0.46
MEN1 O00255 3/20 0.45
LMNA P02545 2/20 0.45
MAPK1 P28482 1/20 0.45
MAPT P10636 5/20 0.44
TSHR P16473 1/20 0.42
PLA2G1B P04054 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
PKM P14618 2/20 0.41
MIF P14174 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2610235 0.93 F2 (0.52) PLA2G7KMT2AALDH1A1F2HPGD
SCHEMBL14390482 0.84 PLA2G7 (0.45) PLA2G7KMT2AALDH1A1F2HPGD
SCHEMBL20169649 0.83 KMT2A (0.47) PLA2G7KMT2AALDH1A1F2HPGD
SCHEMBL6436150 0.83 PLA2G7 (0.44) PLA2G7KMT2AALDH1A1F2HPGD
SCHEMBL12464256 0.78 KMT2A (0.40) PLA2G7KMT2AALDH1A1F2HPGD
SCHEMBL4001149 0.75 ALDH1A1 (0.43) PLA2G7KMT2AALDH1A1F2HPGD
SCHEMBL4001148 0.75 ALDH1A1 (0.43) PLA2G7KMT2AALDH1A1F2HPGD
SCHEMBL18221811 0.74 NPC1 (0.58) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL21261970 0.73 KMT2A (0.46) KMT2AALDH1A1MEN1MAPK1MAPT
SCHEMBL18221803 0.72 GAA (0.59) KMT2AALDH1A1HPGDMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6403720-B1 SUITABLE FOR TIRE, BLENDING A GELLED RUBBER SYNTHESIZED WITH AN ACID ANHYDRIDE ETC, AND A DIENE RUBBER WITHOUT DECREASING ABRASION RESISTANCE, IMPROVED WET PERFORMANCE, DECREASED ROLLING RESISTANCE THE YOKOHAMA RUBBER CO., LTD. (JP) 2002-06-11 US disclosed
EP-0290131-B1 ACRYLIC RUBBER, ACRYLIC RUBBER COMPOSITION AND CURED RUBBER ARTICLE THEREOF JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-05-19 EP disclosed
US-4912186-A Using alkyl acrylate, vinyl compounds in presence of free radical catalyst JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-03-27 US disclosed
EP-0290131-A2 Acrylic rubber, acrylic rubber composition and cured rubber article thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-11-09 EP disclosed