SCHEMBL20169649

SCHEMBL20169649

O=C(ON=C1C=CC(=NOc2ccccc2)C=C1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
MEN1 O00255 2/20 0.47
MAPK1 P28482 1/20 0.47
MAPT P10636 5/20 0.46
PLA2G7 Q13093 2/20 0.44
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
F2 P00734 2/20 0.42
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
PKM P14618 3/20 0.41
CDK5 Q00535 2/20 0.41
CDK5R1 Q15078 2/20 0.41
ALDH1A1 P00352 3/20 0.40
HPGD P15428 2/20 0.40
ATM Q13315 1/20 0.40
PLA2G1B P04054 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
TSHR P16473 1/20 0.40
PARP10 Q53GL7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21261970 0.90 KMT2A (0.46) KMT2AMEN1MAPK1MAPTL3MBTL1
SCHEMBL2610235 0.89 F2 (0.52) KMT2AMEN1MAPK1MAPTPLA2G7
SCHEMBL7638875 0.83 PLA2G7 (0.46) KMT2AMEN1MAPK1MAPTPLA2G7
SCHEMBL14390482 0.81 PLA2G7 (0.45) KMT2AMEN1MAPK1MAPTPLA2G7
SCHEMBL6436150 0.80 PLA2G7 (0.44) KMT2AMEN1MAPK1MAPTPLA2G7
SCHEMBL22795111 0.80 LTA4H (0.41) L3MBTL1ALDH1A1TSHR
SCHEMBL12464256 0.78 KMT2A (0.40) KMT2AMEN1MAPK1MAPTPLA2G7
SCHEMBL18221805 0.72 ALDH1A1 (0.68) KMT2AMEN1MAPK1MAPTNPC1
SCHEMBL18221811 0.72 NPC1 (0.58) KMT2AMEN1MAPTLMNAL3MBTL1
SCHEMBL18221803 0.70 GAA (0.59) KMT2AMEN1MAPK1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11781002-B2 Fluorine-containing elastomer composition for heat dissipation material and sheet thereof DAIKIN INDUSTRIES, LTD. (JP) 2023-10-10 US disclosed
US-20230192984-A1 FLUORINE RUBBER COMPOSITION AND CROSSLINKED FLUORINE RUBBER PRODUCT DAIKIN INDUSTRIES, LTD. (JP) 2023-06-22 US disclosed
US-20200308389-A1 FLUORINE-CONTAINING ELASTOMER COMPOSITION FOR HEAT DISSIPATION MATERIAL AND SHEET THEREOF DAIKIN INDUSTRIES, LTD. (JP) 2020-10-01 US disclosed
US-9976016-B2 Fluororubber composition DAIKIN INDUSTRIES, LTD. (JP) 2018-05-22 US disclosed