Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464361 | 0.88 | CTSC (0.53) | CTSC | |
| SCHEMBL12464294 | 0.78 | OPRM1 (0.57) | — | |
| SCHEMBL12464483 | 0.77 | FCER2 (0.52) | CTSC | |
| SCHEMBL12464201 | 0.76 | CTSC (0.52) | CTSC | |
| SCHEMBL29465522 | 0.75 | ERAP2 (0.53) | — | |
| SCHEMBL22649189 | 0.73 | CTSC (0.60) | CTSC | |
| SCHEMBL10049933 | 0.73 | CTSC (0.60) | CTSC | |
| SCHEMBL29372257 | 0.73 | CTSC (0.60) | CTSC | |
| SCHEMBL22925587 | 0.73 | CTSC (0.60) | CTSC | |
| SCHEMBL9711289 | 0.73 | FOLH1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183358-A1 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE | THE BURNHAM INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |