Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 2/20 | 0.56 |
| ▸ | CCKBR | P32239 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464294 | 0.89 | OPRM1 (0.57) | OPRM1OPRD1 | |
| SCHEMBL12464360 | 0.85 | NPY1R (0.56) | — | |
| SCHEMBL13725698 | 0.84 | ECE1 (0.64) | — | |
| SCHEMBL22133113 | 0.84 | ECE1 (0.64) | — | |
| SCHEMBL30799684 | 0.84 | ECE1 (0.64) | — | |
| SCHEMBL29966716 | 0.83 | OPRM1 (0.72) | OPRM1OPRD1 | |
| SCHEMBL12464361 | 0.82 | CTSC (0.53) | — | |
| SCHEMBL12464362 | 0.82 | — | — | |
| SCHEMBL31722484 | 0.82 | KDM4E (0.62) | — | |
| SCHEMBL29966936 | 0.81 | GHSR (0.67) | OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183358-A1 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE | THE BURNHAM INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |