Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.52 |
| ▸ | F2R | P25116 | 2/20 | 0.48 |
| ▸ | FCER2 | P06734 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464464 | 0.78 | CTSC (0.54) | CTSCFCER2 | |
| SCHEMBL12464088 | 0.77 | CTSC (0.53) | CTSCFCER2 | |
| SCHEMBL12464086 | 0.77 | CTSC (0.51) | CTSCFCER2 | |
| SCHEMBL14534320 | 0.77 | CTSC (0.51) | CTSCFCER2 | |
| SCHEMBL12464474 | 0.77 | CTSC (0.58) | CTSC | |
| SCHEMBL14639989 | 0.77 | CTSC (0.51) | CTSCFCER2 | |
| SCHEMBL30995920 | 0.77 | FCER2 (0.63) | CTSCFCER2 | |
| SCHEMBL12464485 | 0.76 | CTSC (0.47) | CTSC | |
| SCHEMBL12464483 | 0.74 | FCER2 (0.52) | CTSCFCER2 | |
| SCHEMBL12464481 | 0.74 | MC5R (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183358-A1 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE | THE BURNHAM INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |