Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019491 | 0.89 | LMNA (0.44) | LMNAMITFSMN1; SMN2MAPTRECQL | |
| SCHEMBL18012879 | 0.89 | LMNA (0.44) | LMNAMITFSMN1; SMN2MAPTRECQL | |
| SCHEMBL1374699 | 0.89 | LMNA (0.44) | LMNAMITFSMN1; SMN2MAPTRECQL | |
| SCHEMBL6259978 | 0.85 | LMNA (0.41) | LMNAMITFSMN1; SMN2MAPTRECQL | |
| SCHEMBL19968525 | 0.85 | LMNA (0.41) | LMNAMITFSMN1; SMN2MAPTRECQL | |
| SCHEMBL11816203 | 0.85 | HTT (0.44) | LMNAMITFSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL15178109 | 0.85 | LMNA (0.41) | LMNAMITFSMN1; SMN2MAPTRECQL | |
| SCHEMBL16151989 | 0.84 | KDM4E (0.43) | LMNA | |
| SCHEMBL16436869 | 0.83 | HTT (0.45) | LMNARAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL26710849 | 0.83 | LMNA (0.37) | LMNAMITFSMN1; SMN2MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293322-B2 | Surfaces containing coupling activator compounds and reinforced resins produced therefrom | JOHNS MANVILLE (US) | 2012-10-23 | — | — | US | disclosed |
| US-20110180957-A1 | SURFACES CONTAINING COUPLING ACTIVATOR COMPOUNDS AND REINFORCED RESINS PRODUCED THEREFROM | BURGHARDT THOMAS | 2011-07-28 | — | — | US | disclosed |