Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19968525 | 1.00 | LMNA (0.41) | LMNAKMT2AMEN1FAAHABHD16A | |
| SCHEMBL5019491 | 0.95 | LMNA (0.44) | LMNAKMT2AMEN1FAAHABHD16A | |
| SCHEMBL1374699 | 0.95 | LMNA (0.44) | LMNAKMT2AMEN1FAAHABHD16A | |
| SCHEMBL18012879 | 0.95 | LMNA (0.44) | LMNAKMT2AMEN1FAAHABHD16A | |
| SCHEMBL16151509 | 0.93 | PAOX (0.43) | LMNAMITFSMN1; SMN2NAMPTRAB9A | |
| SCHEMBL12326879 | 0.89 | LMNA (0.44) | LMNAKMT2AMEN1MITFSMN1; SMN2 | |
| SCHEMBL15386148 | 0.89 | LMNA (0.37) | LMNAKMT2AMEN1FAAHABHD16A | |
| SCHEMBL21581143 | 0.89 | LMNA (0.33) | LMNAKMT2AMEN1FAAHABHD16A | |
| SCHEMBL12167253 | 0.88 | TPSAB1 (0.43) | LMNAKMT2AMEN1FAAHABHD16A | |
| SCHEMBL9158519 | 0.88 | KDM4E (0.45) | NAMPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853321-B2 | Laser curable polymerisable composition for the protection of hard tissue | DENTSPLY INTERNATIONAL INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20140058010-A1 | LASER CURABLE POLYMERISABLE COMPOSITION FOR THE PROTECTION OF HARD TISSUE | DENTSPLY INTERNATIONAL INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-20080274442-A1 | Laser curable polymerisable composition for the protection of hard tissue | KLEE JOACHIM E | 2008-11-06 | — | — | US | disclosed |
| US-20080274442-A1 | Laser curable polymerisable composition for the protection of hard tissue | KLEE JOACHIM E | 2008-11-06 | — | — | US | disclosed |
| US-20070010597-A1 | Laser curable polymerisable composition for he protection of hard tissue | DENTSPLY RESEARCH AND DEVELOPMENT CORP. (US) | 2007-01-11 | — | — | US | disclosed |
| US-20070010597-A1 | Laser curable polymerisable composition for he protection of hard tissue | DENTSPLY RESEARCH AND DEVELOPMENT CORP. (US) | 2007-01-11 | — | — | US | disclosed |
| EP-1580739-A1 | An object comprising a functional layer | DSM IP Assets B.V. (NL) | 2005-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274442-A1 | Laser curable polymerisable composition for the protection of hard tissue | HSPA2, CDH1, HSPH1 | LMNA 1198/4885KMT2A 1659/4885MEN1 4680/4885 |
| US-20140058010-A1 | LASER CURABLE POLYMERISABLE COMPOSITION FOR THE PROTECTION OF HARD TISSUE | HSPA2, CDH1, HSPH1 | LMNA 1198/4885KMT2A 1659/4885MEN1 4680/4885 |
| US-20070010597-A1 | Laser curable polymerisable composition for he protection of hard tissue | HSPH1, HEATR1, HSPA2 | LMNA 1391/4885KMT2A 1598/4885MEN1 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.