Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879206 | 0.83 | CA12 (0.32) | GABBR2GABBR1MEN1KMT2A | |
| SCHEMBL12376819 | 0.75 | GABBR2 (0.33) | TDP1KDM4EALDH1A1GABBR2GABBR1 | |
| SCHEMBL12398400 | 0.75 | SMN1; SMN2 (0.38) | TDP1KDM4EALDH1A1GABBR2GABBR1 | |
| SCHEMBL9966160 | 0.72 | TDP1 (0.36) | TDP1KDM4EALDH1A1MEN1MAPT | |
| SCHEMBL12119777 | 0.71 | MAPT (0.31) | TDP1KDM4EALDH1A1GABBR2GABBR1 | |
| SCHEMBL2742177 | 0.71 | HRH3 (0.34) | KDM4E | |
| SCHEMBL18470400 | 0.71 | TDP1 (0.31) | TDP1KDM4EALDH1A1MEN1EGFR | |
| SCHEMBL10134937 | 0.70 | TDP1 (0.36) | TDP1KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL2886439 | 0.70 | — | — | |
| SCHEMBL569646 | 0.69 | TDP1 (0.47) | TDP1ALDH1A1GAAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183263-A1 | ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN USING THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2011-07-28 | — | — | US | disclosed |