Styrene

Styrene

SCHEMBL1246542

C=C(C)C(=O)OCC(CC)CCCC.C=Cc1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
CYP3A4 P08684 3/20 0.54
CA2 P00918 1/20 0.54
LMNA P02545 3/20 0.53
MAPK1 P28482 3/20 0.53
TSHR P16473 6/20 0.51
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
TDP1 Q9NUW8 2/20 0.46
ATM Q13315 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KDM4E B2RXH2 1/20 0.39
RECQL P46063 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL10579599 0.98 ALDH1A1 (0.52) ALDH1A1CYP3A4CA2LMNAMAPK1
Styrene SCHEMBL28988056 0.96 ALDH1A1 (0.50) ALDH1A1CYP3A4CA2LMNAMAPK1
Styrene SCHEMBL29158064 0.94 ALDH1A1 (0.49) ALDH1A1CYP3A4CA2LMNAMAPK1
Styrene SCHEMBL8956089 0.92 TSHR (0.55) ALDH1A1CYP3A4CA2LMNAMAPK1
Styrene SCHEMBL1765871 0.91 TSHR (0.57) ALDH1A1CYP3A4CA2LMNAMAPK1
Styrene SCHEMBL7717059 0.90 TSHR (0.58) ALDH1A1CYP3A4CA2LMNAMAPK1
SCHEMBL9504275 0.88 TSHR (0.49) ALDH1A1CYP3A4CA2LMNAMAPK1
Styrene SCHEMBL2352031 0.88 TSHR (0.59) ALDH1A1CYP3A4CA2LMNAMAPK1
Styrene SCHEMBL8083641 0.88 TSHR (0.56) ALDH1A1CYP3A4CA2LMNAMAPK1
Styrene SCHEMBL27467831 0.87 TSHR (0.64) ALDH1A1CYP3A4CA2LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9996019-B1 Cold pressure fix toner compositions and processes XEROX CORPORATION (US) 2018-06-12 US claimed
US-9971265-B1 Toner compositions and processes XEROX CORPORATION (US) 2018-05-15 US claimed
EP-2556020-B1 HYDROPHOBIC SILICA PARTICLES AND METHOD OF PRODUCING SAME CABOT CORP (US) 2020-06-24 EP disclosed
EP-3370117-B1 COLD PRESSURE FIX TONER COMPOSITIONS AND PROCESSES XEROX CORP (US) 2019-11-13 EP disclosed
EP-3367170-B1 TONER COMPOSITIONS XEROX CORP (US) 2019-09-25 EP disclosed
EP-3370117-A1 COLD PRESSURE FIX TONER COMPOSITIONS AND PROCESSES Xerox Corporation (US) 2018-09-05 EP disclosed
EP-3367170-A1 TONER COMPOSITIONS AND PROCESSES Xerox Corporation (US) 2018-08-29 EP disclosed
US-9996019-B1 Cold pressure fix toner compositions and processes XEROX CORPORATION (US) 2018-06-12 US disclosed
US-9971265-B1 Toner compositions and processes XEROX CORPORATION (US) 2018-05-15 US disclosed
US-9581922-B2 Treated fumed silica CABOT CORPORATION (US) 2017-02-28 US disclosed
US-20150079512-A1 Treated Fumed Silica CABOT CORPORATION 2015-03-19 US disclosed
US-5455137-A Toner and base treated fumed silica; noncaking, improved fluidity INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1995-10-03 US disclosed
EP-0664493-A1 Friction charge-providing member for positively-chargeable toner HODOGAYA CHEMICAL CO., LTD. (JP) 1995-07-26 EP disclosed
EP-0655658-A2 Friction charge-providing member for positively-chargeable toner HODOGAYA CHEMICAL CO., LTD. (JP) 1995-05-31 EP disclosed
US-5382491-A CONTAINING A NONCONDUCTIVE, BASE TREATED POLYANILINE CHARGE CONTROL AGENT FOR USE IN ELECTROGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1995-01-17 US disclosed
EP-0270063-B1 Developer for developing electrostatic latent image and image forming method CANON KK (JP) 1994-06-29 EP disclosed
US-4906548-A Developer for developing electrostatic latent image and image forming method CANON KABUSHIKI KAISHA (JP) 1990-03-06 US disclosed
US-4868084-A TREATED SILICA POWDER, HYDROPHOBIC, NEGATIVELY CHARGEABLE CANON KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed
EP-0270063-A2 Developer for developing electrostatic latent image and image forming method CANON KABUSHIKI KAISHA (JP) 1988-06-08 EP disclosed
US-4315983-A 2,6-Di-tert-butyl-4-substituted thiopyrylium salt, process for production of same, and a photoconductive composition containing same FUJI PHOTO FILM CO., LTD. (JP) 1982-02-16 US disclosed