SCHEMBL1246549

SCHEMBL1246549

OCC1=CCC(CO)CC1

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
ALOX15 P16050 1/20 0.52
CYP1B1 Q16678 1/20 0.52
ALDH1A1 P00352 1/20 0.52
ESR2 Q92731 2/20 0.50
ESR1 P03372 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12186319 0.83 ESR2 (0.47) CES2ALOX15CYP1B1ALDH1A1ESR2
SCHEMBL14647807 0.83 ESR2 (0.47) CES2ALOX15CYP1B1ALDH1A1ESR2
SCHEMBL14730407 0.83 CES2 (0.53) CES2ALOX15CYP1B1ALDH1A1ESR2
SCHEMBL17581520 0.82 ALDH1A1 (0.39) CES2ALOX15CYP1B1ALDH1A1ESR2
SCHEMBL11312220 0.76 ESR2 (0.41) CES2ALOX15CYP1B1ALDH1A1ESR2
SCHEMBL15943521 0.76 ALDH1A1 (0.46) CES2ALOX15CYP1B1ALDH1A1ESR2
SCHEMBL9414358 0.76 ESR2 (0.41) CES2ALOX15CYP1B1ALDH1A1ESR2
SCHEMBL22019179 0.76
SCHEMBL14724819 0.76
SCHEMBL10084343 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151868-A2 POLYCARBONATE-BASED VITRIMER MATERIALS AND CORRESPONDING METHODS THE UNIVERSITY OF AKRON (US) 2024-07-18 WO claimed
US-9062197-B2 Polyester blends EASTMAN CHEMICAL COMPANY (US) 2015-06-23 US claimed
US-8845935-B2 Method for cast molding contact lenses NOVARTIS AG (CH) 2014-09-30 US claimed
US-20090230575-A1 Method for cast molding contact lenses ALCON INC. (CH) 2009-09-17 US claimed
US-6706842-B1 Crosslinked polyester copolymers DUAN JIWEN F (US) 2004-03-16 US claimed
JP-54131689-A None JP disclosed
JP-9185240-A None JP disclosed
EP-4725976-A1 POLYMERIC CYCLOALIPHATIC EPOXIDES ARKEMA FRANCE (FR) 2026-04-15 EP disclosed
US-20260015499-A1 POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2026-01-15 US disclosed
EP-4065637-B1 FLAME-RETARDANT POLYESTER MOLDING COMPOSITIONS BASF SE (DE) 2026-01-07 EP disclosed
EP-4642853-A1 POLYCARBONATE COMPOSITION Covestro Deutschland AG (DE) 2025-11-05 EP disclosed
US-20250257208-A1 Polycarbonate Composition COVESTRO DEUTSCHLAND AG (DE) 2025-08-14 US disclosed
EP-0046731-B1 PROCESS FOR THE PRODUCTION OF DI- AND POLYALLYL ETHERS CIBA-GEIGY AG (CH) 1984-10-03 EP disclosed
US-4433179-A Process for the preparation of di- and poly-allyl ethers CIBA-GEIGY CORPORATION (US) 1984-02-21 US disclosed
EP-0046731-A1 Process for the production of di- and polyallyl ethers CIBA-GEIGY AG (CH) 1982-03-03 EP disclosed
US-4184035-A Process for neutralizing halogenated acid intermediates for polyester production VELSICOL CHEMICAL CORPORATION (US) 1980-01-15 US disclosed
JP-S54131689-A PREPARATION OF CROSSLINKED AROMATIC POLYESTER TEIJIN LTD 1979-10-12 JP disclosed
US-4094859-A MANGANESE, IRON, COBALT, NICKEL, COPPER, OR ZINC SULFATE AMERICAN CYANAMID COMPANY (US) 1978-06-13 US disclosed
US-4093599-A WITH A DIOL; SULFURIC AND PHOSPHORIC ACIDS AS CATALYSTS AMERICAN CYANAMID COMPANY (US) 1978-06-06 US disclosed
US-3951927-A Vulcanizable elastomers from polythiodiethanol AMERICAN CYANAMID COMPANY (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015499-A1 POLYCARBONATE COMPOSITION BPNT1, COL1A1, PBRM1 CES2 2973/4885ALOX15 1567/4885CYP1B1 159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.