Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12407044 | 0.82 | CYP2C19 (0.60) | KMT2AAKR1C3TPSAB1PRMT1ALDH1A1 | |
| SCHEMBL13637021 | 0.82 | PRMT1 (0.54) | KMT2AAKR1C3TPSAB1PRMT1ALDH1A1 | |
| SCHEMBL1246677 | 0.81 | CA2 (0.48) | KMT2AAKR1C3USP2 | |
| Hydrochloric Acid SCHEMBL4636067 | 0.81 | CYP2C19 (0.58) | KMT2AAKR1C3TPSAB1PRMT1ALDH1A1 | |
| SCHEMBL21051622 | 0.80 | USP2 (0.68) | KMT2AUSP2ALDH1A1MAPK1TDP1 | |
| SCHEMBL18498633 | 0.80 | ATM (0.72) | KMT2AAKR1C3USP2ALDH1A1CYP2C19 | |
| SCHEMBL4615322 | 0.78 | KEAP1 (0.69) | PRMT1ALDH1A1HTR6CYP1A2HDAC2 | |
| SCHEMBL1246685 | 0.77 | SCN9A (0.52) | KMT2AAKR1C3USP2ALDH1A1CYP2C19 | |
| Hydrochloric Acid SCHEMBL4010772 | 0.77 | KEAP1 (0.67) | PRMT1ALDH1A1HTR6CYP1A2HDAC2 | |
| SCHEMBL4615715 | 0.76 | HTR6 (0.53) | KMT2ATPSAB1PRMT1ALDH1A1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2286221-A2 | METHODS FOR ASSAYING COMPOUNDS OR AGENTS FOR ABILITY TO DISPLACE POTENT LIGANDS OF HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | Cayman Chemical Company (US) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009140364-A2 | METHODS FOR ASSAYING COMPOUNDS OR AGENTS FOR ABILITY TO DISPLACE POTENT LIGANDS OF HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | CAYMAN CHEMICAL COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |