Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335311 | 0.72 | NOTUM (0.59) | NOTUM | |
| SCHEMBL12465637 | 0.72 | GNG2 (0.38) | NOTUM | |
| SCHEMBL3819800 | 0.69 | RXRA (0.49) | — | |
| SCHEMBL11988475 | 0.69 | NOTUM (0.42) | NOTUM | |
| SCHEMBL450030 | 0.68 | HSD17B3 (0.44) | NOTUM | |
| SCHEMBL12465677 | 0.68 | MCHR1 (0.32) | NOTUM | |
| SCHEMBL12465974 | 0.67 | NOTUM (0.33) | NOTUM | |
| SCHEMBL5626609 | 0.66 | NOTUM (0.42) | NOTUM | |
| SCHEMBL15388711 | 0.66 | GNG2 (0.38) | NOTUM | |
| SCHEMBL20883595 | 0.65 | HSP90AA1 (0.41) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670744-A1 | PYRROLE DERIVATIVES USED AS MODULATORS OF ALPHA7 NACHR | Lupin Limited (IN) | 2013-12-11 | — | — | EP | disclosed |
| WO-2012104782-A1 | PYRROLE DERIVATIVES USED AS MODULATORS OF ALPHA7 NACHR | LUPIN LIMITED (IN) | 2012-08-09 | — | — | WO | disclosed |