Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976253 | 0.87 | PRKCZ (0.50) | HSD17B10PRKCZALDH1A1MAPTMEN1 | |
| SCHEMBL1799330 | 0.82 | KMT2A (0.69) | HSD17B10PRKCZALDH1A1MAPTMEN1 | |
| SCHEMBL12466203 | 0.82 | HSD17B10 (0.51) | HSD17B10PRKCZALDH1A1MAPTMEN1 | |
| SCHEMBL4932598 | 0.82 | HSD17B10 (0.51) | HSD17B10PRKCZALDH1A1MAPTMEN1 | |
| SCHEMBL12466271 | 0.82 | ADORA1 (0.49) | HSD17B10PRKCZALDH1A1MAPTMEN1 | |
| SCHEMBL2367950 | 0.81 | PRKCZ (0.63) | HSD17B10PRKCZALDH1A1MAPTMEN1 | |
| SCHEMBL3980156 | 0.81 | PRKCZ (0.45) | HSD17B10PRKCZALDH1A1MAPTMEN1 | |
| SCHEMBL27729284 | 0.81 | HSD17B10 (0.50) | HSD17B10PRKCZALDH1A1MAPTMEN1 | |
| SCHEMBL689202 | 0.80 | PRKCZ (0.73) | HSD17B10PRKCZALDH1A1MAPTMEN1 | |
| SCHEMBL8188234 | 0.80 | KMT2A (0.65) | HSD17B10PRKCZALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012100732-A1 | RETINOID-RELATED ORPHAN RECEPTOR GAMMA MODULATORS, COMPOSITION CONTAINING THEM AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2012-08-02 | — | — | WO | disclosed |
| CN-101351453-A | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL (JP) | 2009-01-21 | — | — | CN | disclosed |