Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | RORB | Q92753 | 5/20 | 0.46 |
| ▸ | RORC | P51449 | 4/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980569 | 0.88 | ADORA1 (0.61) | ADORA1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL28599809 | 0.83 | PRKCZ (0.48) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3972275 | 0.83 | RORB (0.49) | ADORA1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL3974980 | 0.82 | ALDH1A1 (0.65) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12465745 | 0.82 | HSD17B10 (0.51) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1799330 | 0.79 | KMT2A (0.69) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4932598 | 0.79 | HSD17B10 (0.51) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12466203 | 0.79 | HSD17B10 (0.51) | ADORA1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6926065 | 0.78 | MPL (0.50) | HSD17B10ALDH1A1KDM4EHPGDPRKCZ | |
| SCHEMBL27729284 | 0.78 | HSD17B10 (0.50) | HSD17B10ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012100732-A1 | RETINOID-RELATED ORPHAN RECEPTOR GAMMA MODULATORS, COMPOSITION CONTAINING THEM AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2012-08-02 | — | — | WO | disclosed |