Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980156 | 0.88 | PRKCZ (0.45) | PRKCZALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL12465745 | 0.87 | HSD17B10 (0.51) | PRKCZALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3980970 | 0.85 | ALDH1A1 (0.65) | PRKCZALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3976339 | 0.85 | PRKCZ (0.58) | PRKCZALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3976445 | 0.84 | ALDH1A1 (0.50) | PRKCZALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3975112 | 0.84 | PRKCZ (0.50) | PRKCZALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3980569 | 0.83 | ADORA1 (0.61) | PRKCZALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3975901 | 0.81 | ALDH1A1 (0.73) | PRKCZALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3979142 | 0.80 | ALDH1A1 (0.65) | PRKCZALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3974068 | 0.77 | CNR2 (0.51) | PRKCZALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |