Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALAD | P13716 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10151048 | 0.78 | ALAD (0.52) | ALADMAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL12466215 | 0.78 | ALDH1A1 (0.47) | MAPTRAB9AALDH1A1PRKCZMEN1 | |
| SCHEMBL2897323 | 0.77 | ALDH1A1 (0.45) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL12465675 | 0.77 | ALAD (0.50) | ALADMAPTRAB9ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL12466040 | 0.76 | ALDH1A1 (0.53) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3258545 | 0.76 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL18869535 | 0.74 | ALAD (0.52) | ALADMAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15674639 | 0.73 | — | — | |
| SCHEMBL4533683 | 0.71 | AHR (0.56) | MAPTRAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL18858485 | 0.69 | ALAD (0.47) | ALADMAPTRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012100732-A1 | RETINOID-RELATED ORPHAN RECEPTOR GAMMA MODULATORS, COMPOSITION CONTAINING THEM AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2012-08-02 | — | — | WO | disclosed |