Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KDM5C | P41229 | 1/20 | 0.52 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243433 | 0.83 | KDM4E (0.50) | KDM4EKDM5CPHF8KDM2ACTSD | |
| SCHEMBL13498565 | 0.81 | GAA (0.50) | KDM4EKDM5CPHF8KDM2ACTSD | |
| SCHEMBL2618708 | 0.76 | KDM4E (0.43) | KDM4EKDM5CPHF8KDM2ACTSD | |
| SCHEMBL13498571 | 0.76 | KDM4E (0.44) | KDM4EKDM5CPHF8KDM2ACTSD | |
| SCHEMBL27004520 | 0.76 | PAOX (0.45) | ALDH1A1ECE1TSHRMEN1KMT2A | |
| SCHEMBL4525713 | 0.75 | CTSD (0.41) | KDM4EKDM5CPHF8KDM2ACTSD | |
| SCHEMBL20470027 | 0.75 | ALDH1A1 (0.50) | KDM4EKDM5CPHF8KDM2ACTSD | |
| SCHEMBL141621 | 0.75 | KDM4E (0.71) | KDM4EKDM5CPHF8KDM2ACTSD | |
| Adipic Acid SCHEMBL28675238 | 0.75 | KDM4E (0.71) | KDM4EKDM5CPHF8KDM2ACTSD | |
| SCHEMBL9717419 | 0.75 | ECE1 (0.60) | KDM4EECE1ATMTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011019882-A1 | NANOSTRUCTURE-BETA-BLOCKER CONJUGATES | WILLIAM MARSH RICE UNIVERSITY (US) | 2011-02-17 | — | — | WO | disclosed |