⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15309066 | 0.71 | — | — | |
| SCHEMBL18536367 | 0.71 | — | — | |
| SCHEMBL7952252 | 0.71 | — | — | |
| SCHEMBL19493420 | 0.71 | — | — | |
| SCHEMBL10328064 | 0.71 | — | — | |
| SCHEMBL18702407 | 0.69 | CA2 (0.31) | — | |
| SCHEMBL7947821 | 0.66 | — | — | |
| SCHEMBL469670 | 0.66 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL22077666 | 0.66 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL7990770 | 0.65 | POLB (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016147197-A1 | A NOVEL PROCESS FOR PREPARING (2S,3R,4R,5S,6R)-2-[4-CHLORO-3-(4-ETHOXYBENZYL)PHENY 1] -6-(HY DROXY METHYL)TETRAHYDRO-2H-PY RAN-3,4,5-TRIOL AND ITS AMORPHOUS FORM | HARMAN FINOCHEM LIMITED (IN) | 2016-09-22 | — | — | WO | claimed |
| CN-117362257-A | Intermediate for preparing SGLT inhibitor, and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-115716821-A | Method for continuously producing englezin by using microchannel reactor | 恒升德康(南京)医药科技有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-113651803-B | Process for producing diphenylmethane derivative | 株式会社大熊制药 | 2022-10-28 | — | — | CN | disclosed |
| CN-110551088-B | Deuterium-modified benzyl-4-chlorophenyl C-glycoside derivatives | 北京惠之衡生物科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-113651803-A | Process for producing diphenylmethane derivative | 株式会社大熊制药 | 2021-11-16 | — | — | CN | disclosed |
| CN-109311861-B | Process for producing diphenylmethane derivative | 株式会社大熊制药 | 2021-08-24 | — | — | CN | disclosed |
| CN-108203432-B | Glucopyranosyl derivative and application thereof in medicine | 宜昌东阳光长江药业股份有限公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-107311992-B | C-aryl glucoside derivative, preparation method and application thereof in medicine | 上海研健新药研发有限公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-106083943-B | Glucopyranosyl derivative and preparation method and application thereof | 广东东阳光药业有限公司 | 2020-01-14 | — | — | CN | disclosed |
| CN-110551088-A | deuterium-modified benzyl-4-chlorophenyl C-glycoside derivatives | XUANZHU BEIJING MEDICINE TECH CO LTD | 2019-12-10 | — | — | CN | disclosed |
| WO-2017060924-A1 | A NOVEL PIPECOLIC ACID CO-CRYSTAL OF CANAGLIFLOZIN AND PROCESS FOR THE PREPARATION THEREOF | HARMAN FINOCHEM LIMITED (IN) | 2017-04-13 | — | — | WO | disclosed |
| WO-2016147197-A1 | A NOVEL PROCESS FOR PREPARING (2S,3R,4R,5S,6R)-2-[4-CHLORO-3-(4-ETHOXYBENZYL)PHENY 1] -6-(HY DROXY METHYL)TETRAHYDRO-2H-PY RAN-3,4,5-TRIOL AND ITS AMORPHOUS FORM | HARMAN FINOCHEM LIMITED (IN) | 2016-09-22 | — | — | WO | disclosed |
| EP-2604612-B1 | C-ARYL GLUCOSIDE DERIVATIVES, PREPARATION RPOCESS AND PHARMACEUTICAL USE THEREOF | SHANGHAI HENGRUI PHARM CO LTD (CN) | 2016-04-20 | — | — | EP | disclosed |
| EP-2604612-A1 | C-ARYL GLUCOSIDE DERIVATIVES, PREPARATION RPOCESS AND PHARMACEUTICAL USE THEREOF | Shanghai Hengrui Pharmaceutical Co. Ltd. (CN) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |