SCHEMBL12467622

SCHEMBL12467622

COc1ccc(CP(=O)(C(C)O)C(C)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.47
SLC6A4 P31645 1/20 0.46
ANPEP P15144 2/20 0.44
ERAP2 Q6P179 2/20 0.44
ALDH1A1 P00352 3/20 0.44
HTT P42858 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
IDO1 P14902 1/20 0.42
ACACB O00763 1/20 0.42
TSHR P16473 1/20 0.42
F2RL1 P55085 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10067436 0.78 FDPS (0.43) ANPEPERAP2ALDH1A1NPC1RAB9A
SCHEMBL9973915 0.77 HPGD (0.50) ANPEPNPC1RAB9ATSHR
SCHEMBL11123144 0.77 ANPEP (0.49) LDHAANPEPERAP2HTTIDO1
SCHEMBL914654 0.77 ANPEP (0.53) LDHAANPEPERAP2HTTIDO1
SCHEMBL9687342 0.77 IDO1 (0.52) LDHASLC6A4ALDH1A1HTTSMN1; SMN2
SCHEMBL9486229 0.73 CMA1 (0.50) LDHASLC6A4ALDH1A1HTTSMN1; SMN2
SCHEMBL12218512 0.73 IDO1 (0.48) LDHASLC6A4ALDH1A1HTTSMN1; SMN2
Butane SCHEMBL3373014 0.73 ENPP2 (0.54) LDHAANPEPERAP2HTTIDO1
SCHEMBL12467618 0.72 THRB (0.49) ALDH1A1SMN1; SMN2TSHR
SCHEMBL914038 0.72 ANPEP (0.44) LDHASLC6A4ANPEPERAP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7985519-B2 Aromatic polycarbonate, electrophotographic photoreceptor, and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2011-07-26 US disclosed
US-7625681-B2 Asymmetric bis-hydroxyenamine compound, electrophotographic photoreceptor and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2009-12-01 US disclosed
US-20080199215-A1 AROMATIC POLYCARBONATE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS SHARP KABUSHIKI KAISHA (JP) 2008-08-21 US disclosed