Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17187309 | 1.00 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2TSHRALDH1A1 | |
| SCHEMBL18416708 | 1.00 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2TSHRALDH1A1 | |
| SCHEMBL17187311 | 1.00 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2TSHRALDH1A1 | |
| SCHEMBL17187310 | 1.00 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2TSHRALDH1A1 | |
| SCHEMBL18421219 | 1.00 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2TSHRALDH1A1 | |
| Monomethyl Fumarate SCHEMBL10715286 | 0.93 | HCAR2 (0.57) | HCAR2KEAP1NFE2L2TSHRALDH1A1 | |
| SCHEMBL18416709 | 0.92 | HCAR2 (0.59) | HCAR2KEAP1NFE2L2TSHRALDH1A1 | |
| SCHEMBL17187303 | 0.92 | HCAR2 (0.59) | HCAR2KEAP1NFE2L2TSHRALDH1A1 | |
| Tegomil Fumarate SCHEMBL17187305 | 0.92 | HCAR2 (0.59) | HCAR2KEAP1NFE2L2TSHRALDH1A1 | |
| SCHEMBL17187302 | 0.92 | HCAR2 (0.59) | HCAR2KEAP1NFE2L2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239473-A1 | NEW DERIVATIVES OF LICOFELONE | ALBRECHT WOLFGANG (DE) | 2020-07-30 | — | — | US | disclosed |
| US-20200239473-A1 | NEW DERIVATIVES OF LICOFELONE | ALBRECHT WOLFGANG (DE) | 2020-07-30 | — | — | US | disclosed |
| EP-3131633-B1 | MMF-DERIVATIVES OF ETHYLENEGLYCOLS | ALBRECHT WOLFGANG (DE) | 2020-03-04 | — | — | EP | disclosed |
| US-20180305292-A1 | DERIVATIVES OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS | ALBRECHT WOLFGANG (DE) | 2018-10-25 | — | — | US | disclosed |
| EP-3365343-A1 | NEW DERIVATIVES OF LICOFELONE | ratiopharm GmbH (DE) | 2018-08-29 | — | — | EP | disclosed |
| EP-3365023-A1 | DERIVATIVES OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS | ratiopharm GmbH (DE) | 2018-08-29 | — | — | EP | disclosed |
| US-9969674-B2 | MMF-derivatives of ethyleneglycols | RATIOPHARM GMBH (DE) | 2018-05-15 | — | — | US | disclosed |
| US-9969674-B2 | MMF-derivatives of ethyleneglycols | RATIOPHARM GMBH (DE) | 2018-05-15 | — | — | US | disclosed |
| US-9969674-B2 | MMF-derivatives of ethyleneglycols | RATIOPHARM GMBH (DE) | 2018-05-15 | — | — | US | disclosed |
| WO-2017068052-A1 | DERIVATIVES OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS | RATIOPHARM GMBH (DE) | 2017-04-27 | — | — | WO | disclosed |
| WO-2017068053-A1 | NEW DERIVATIVES OF LICOFELONE | RATIOPHARM GMBH (DE) | 2017-04-27 | — | — | WO | disclosed |
| WO-2017068053-A1 | NEW DERIVATIVES OF LICOFELONE | RATIOPHARM GMBH (DE) | 2017-04-27 | — | — | WO | disclosed |
| WO-2017068052-A1 | DERIVATIVES OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS | RATIOPHARM GMBH (DE) | 2017-04-27 | — | — | WO | disclosed |
| EP-3131633-A1 | MMF-DERIVATIVES OF ETHYLENEGLYCOLS | ratiopharm GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
| US-20170029357-A1 | MMF-DERIVATIVES OF ETHYLENEGLYCOLS | ALBRECHT, WOLFGANG (DE) | 2017-02-02 | — | — | US | disclosed |
| US-20170029357-A1 | MMF-DERIVATIVES OF ETHYLENEGLYCOLS | ALBRECHT, WOLFGANG (DE) | 2017-02-02 | — | — | US | disclosed |
| US-20170029357-A1 | MMF-DERIVATIVES OF ETHYLENEGLYCOLS | ALBRECHT, WOLFGANG (DE) | 2017-02-02 | — | — | US | disclosed |
| WO-2015158817-A1 | MMF-DERIVATIVES OF ETHYLENEGLYCOLS | RATIOPHARM GMBH (DE) | 2015-10-22 | — | — | WO | disclosed |
| EP-2627721-A1 | HIGH SOLIDS ANTIFOULING PAINT COMPOSITION | Hempel A/S (DK) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012048712-A1 | HIGH SOLIDS ANTIFOULING PAINT COMPOSITION | HEMPEL A/S (DK) | 2012-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239473-A1 | NEW DERIVATIVES OF LICOFELONE | CYP51A1, CYP3A5, LITAF | HCAR2 509/4885KEAP1 2402/4885NFE2L2 3101/4885 |
| US-20180305292-A1 | DERIVATIVES OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS | TNF, PTGES, PTGES2 | HCAR2 29/4885KEAP1 1108/4885NFE2L2 249/4885 |
| US-20170029357-A1 | MMF-DERIVATIVES OF ETHYLENEGLYCOLS | MGMT, PMM2, HLA-DRB1 | HCAR2 455/4885KEAP1 425/4885NFE2L2 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.