Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | FBP1 | P09467 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246880 | 1.00 | PTGS2 (0.51) | PTGS2HTTFBP1GAAEGFR | |
| SCHEMBL25182595 | 0.87 | FBP1 (0.50) | PTGS2HTTFBP1GAAEGFR | |
| SCHEMBL25179132 | 0.85 | FBP1 (0.49) | PTGS2HTTFBP1GAAEGFR | |
| SCHEMBL29896434 | 0.84 | EGFR (0.43) | PTGS2HTTFBP1GAAEGFR | |
| SCHEMBL25186178 | 0.83 | MAPT (0.49) | PTGS2HTTFBP1GAAEGFR | |
| SCHEMBL31238218 | 0.82 | ALDH1A1 (0.64) | PTGS2HTTFBP1GAAEGFR | |
| SCHEMBL1245811 | 0.82 | ALDH1A1 (0.64) | PTGS2HTTFBP1GAAEGFR | |
| SCHEMBL1245812 | 0.82 | ALDH1A1 (0.64) | PTGS2HTTFBP1GAAEGFR | |
| SCHEMBL29896425 | 0.82 | EGFR (0.42) | PTGS2HTTFBP1GAAEGFR | |
| SCHEMBL25173453 | 0.81 | EGFR (0.48) | PTGS2HTTFBP1GAAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947849-B2 | UV-absorbers for ophthalmic lens materials | ALCON, INC. (CH) | 2011-05-24 | — | — | US | disclosed |
| US-20110046259-A1 | UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-02-24 | — | — | US | disclosed |
| US-7884228-B1 | intraocular lens comprising 2-(2-methoxy-4-(2-nitroprop-1-enyl)phenoxy)ethyl methacrylate monomeric ultraviolet light absorber; particularly useful in implantable lenses, such as intraocular lenses; copolymerizable | ALCON, INC. (CH) | 2011-02-08 | — | — | US | disclosed |