Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3820690 | 0.89 | TDP1 (0.52) | LMNATDP1FFAR1KEAP1NPC1 | |
| Hydrochloric Acid SCHEMBL4733599 | 0.88 | TDP1 (0.50) | LMNATDP1FFAR1KEAP1NPC1 | |
| SCHEMBL31269978 | 0.80 | LMNA (0.62) | LMNATDP1FFAR1NPC1RAB9A | |
| SCHEMBL9667394 | 0.78 | MAPT (0.51) | LMNATDP1FFAR1KEAP1MAPK1 | |
| SCHEMBL3584403 | 0.76 | KEAP1 (0.63) | TDP1FFAR1KEAP1ALDH1A1MAPK1 | |
| SCHEMBL22266190 | 0.74 | TSHR (0.48) | LMNATDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL22266205 | 0.74 | LMNA (0.53) | LMNATDP1FFAR1KEAP1NPC1 | |
| SCHEMBL906396 | 0.74 | TSHR (0.52) | LMNATDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL3594705 | 0.73 | TDP1 (0.52) | LMNATDP1FFAR1KEAP1NPC1 | |
| Acetone SCHEMBL27310709 | 0.71 | ALDH1A1 (0.57) | LMNATDP1FFAR1KEAP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627639-A1 | N-OPTIONALLY SUBSTITUTED ARYL-2-OLIGOMER-3-ALKOXYPROPIONAMIDES | Nektar Therapeutics (US) | 2013-08-21 | — | — | EP | claimed |
| WO-2012051551-A1 | N-OPTIONALLY SUBSTITUTED ARYL-2-OLIGOMER-3-ALKOXYPROPIONAMIDES | NEKTAR THERAPEUTICS (US) | 2012-04-19 | — | — | WO | claimed |