Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | MAP3K9 | P80192 | 2/20 | 0.36 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | MAP3K10 | Q02779 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836057 | 0.69 | AURKA (0.57) | AURKAKDRMAP3K9MAP3K11PIK3CD | |
| SCHEMBL3840660 | 0.69 | KDR (0.62) | AURKAKDRMAP3K9MAP3K11LMNA | |
| SCHEMBL3835796 | 0.68 | MAP3K9 (0.38) | AURKAKDRMAP3K9MAP3K11PIK3CD | |
| SCHEMBL12469179 | 0.66 | BRD4 (0.34) | AURKAKDR | |
| SCHEMBL20992951 | 0.65 | CLK4 (0.47) | KDRMAP3K9MAP3K11PIK3CDPIK3CA | |
| SCHEMBL20992953 | 0.65 | MAP3K9 (0.47) | MAP3K9MAP3K11NTRK1FYNFLT4 | |
| SCHEMBL15814826 | 0.59 | ALDH1A1 (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL743016 | 0.59 | MCL1 (0.59) | LMNAALDH1A1 | |
| SCHEMBL8466568 | 0.59 | KDR (0.44) | AURKAKDRMAP3K9MAP3K11NTRK1 | |
| SCHEMBL3839919 | 0.58 | GCK (0.34) | MAP3K9MAP3K11NTRK1FYNFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |