Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.58 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.57 |
| ▸ | FEN1 | P39748 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20057645 | 0.89 | HPGD (0.72) | HPGDLMNATSHRHSD17B2ERCC5 | |
| SCHEMBL27616105 | 0.82 | HPGD (0.66) | HPGDLMNATSHRERCC5FEN1 | |
| SCHEMBL2199255 | 0.82 | CES2 (0.65) | TSHRHSD17B2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12688050 | 0.82 | HSD17B2 (0.87) | HPGDLMNATSHRHSD17B2ERCC5 | |
| SCHEMBL8479394 | 0.81 | HPGD (0.64) | HPGDLMNATSHRERCC5FEN1 | |
| SCHEMBL3639698 | 0.81 | SMN1; SMN2 (0.74) | HPGDLMNATSHRERCC5FEN1 | |
| SCHEMBL23289051 | 0.80 | HPGD (0.62) | HPGDLMNATSHRERCC5FEN1 | |
| SCHEMBL3720494 | 0.80 | PARP1 (0.67) | HPGDLMNATSHRERCC5FEN1 | |
| SCHEMBL30913837 | 0.80 | HPGD (0.62) | HPGDLMNATSHRERCC5FEN1 | |
| SCHEMBL7825137 | 0.80 | PLAU (0.66) | HPGDLMNATSHRERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765667-B2 | HCV protease inhibitors | EISSENSTAT MICHAEL (US) | 2014-07-01 | — | — | US | disclosed |
| US-20110182854-A1 | HCV PROTEASE INHIBITORS | SEQUOIA PHARMACEUTICALS, INC. (US) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182854-A1 | HCV PROTEASE INHIBITORS | SERPINB1, CTSC, HPN | HPGD 1339/4885LMNA 1932/4885TSHR 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.