Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.65 |
| ▸ | CES1 | P23141 | 1/20 | 0.65 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30870831 | 0.87 | CES2 (0.67) | CES2CES1PARP1HSD17B2NPC1 | |
| SCHEMBL2540656 | 0.87 | CES2 (0.67) | CES2CES1PARP1HSD17B2NPC1 | |
| SCHEMBL307622 | 0.84 | CES2 (0.62) | CES2CES1PARP1HSD17B2NPC1 | |
| SCHEMBL9876838 | 0.83 | AKR1C3 (0.64) | NPC1SMN1; SMN2KDM4E | |
| SCHEMBL3279166 | 0.82 | KMT2A (0.53) | MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL12469448 | 0.82 | HPGD (0.70) | HSD17B2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14319078 | 0.81 | CES2 (0.59) | CES2CES1PARP1HSD17B2NPC1 | |
| SCHEMBL21425705 | 0.81 | MEN1 (0.60) | CES2CES1PARP1HSD17B2NPC1 | |
| SCHEMBL2353790 | 0.81 | CES2 (0.59) | CES2CES1PARP1HSD17B2NPC1 | |
| SCHEMBL1436162 | 0.81 | ALDH1A1 (0.46) | CES2CES1MEN1KMT2AABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977383-B2 | Containing alkali ions, electrolytes, a buffer, polyol, saccharide and hydroxamic acid derivatives | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2011-07-12 | — | — | US | disclosed |
| US-20030215781-A1 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030215781-A1 | Protective solutions for organs | GLS, CA1, SI | CES2 1601/4885CES1 1096/4885PARP1 1108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.