Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30863406 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1NAPRTMAPTSMN1; SMN2 | |
| SCHEMBL2902900 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1NAPRTMAPTSMN1; SMN2 | |
| SCHEMBL16414377 | 0.79 | KDM4E (0.45) | PARP1KDM4EALDH1A1NAPRTMAPT | |
| SCHEMBL4186883 | 0.78 | KDM4E (0.65) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL310265 | 0.77 | NAPRT (0.70) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1369444 | 0.77 | PARP1 (0.58) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30901792 | 0.77 | NAPRT (0.70) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL164482 | 0.77 | PARP1 (0.58) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31513532 | 0.77 | PARP1 (0.58) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL773980 | 0.77 | PARP1 (0.58) | PARP1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2911513-A1 | COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE | Bayer Cropscience LP (US) | 2015-09-02 | — | — | EP | claimed |
| WO-2014066877-A1 | COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE | BAYER CROPSCIENCE LP (US) | 2014-05-01 | — | — | WO | claimed |
| CN-110267670-B | Agent for ion-transcellular transporter in intestinal tract, chloride channel activator, preventive or therapeutic agent for kidney disease, or defecation promoter | 表飞鸣制药株式会社 | 2023-08-15 | — | — | CN | disclosed |
| US-11504439-B2 | Radioactive compound for diagnosis of malignant melanoma and use thereof | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2022-11-22 | — | — | US | disclosed |
| WO-2019068810-A1 | USE OF COMPOSITIONS COMPRISING FLUOPYRAM FOR ENHANCING ANTIOXIDATIVE FITNESS OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-04-11 | — | — | WO | disclosed |
| WO-2018057588-A1 | FURO[3,2-B]PYRIDINE COMPOUNDS USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-03-29 | — | — | WO | disclosed |
| US-20180057505-A1 | BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY | VERTEX PHARMACEUTICALS INCORPORATED | 2018-03-01 | — | — | US | disclosed |
| WO-2016154075-A1 | BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2016-09-29 | — | — | WO | disclosed |
| CN-104745693-A | SOYBEAN EVENT SYHT0H2 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF | SYNGENTA PARTICIPATIONS AG | 2015-07-01 | — | — | CN | disclosed |
| EP-2736333-A1 | SEED DRESSING FOR CONTROLLING PHYTOPATHOGENIC FUNGI | Bayer Intellectual Property GmbH (DE) | 2014-06-04 | — | — | EP | disclosed |
| CN-103597077-A | Soybean event SYHT0H2 and compositions and methods for detection thereof | SYNGENTA PARTICIPATIONS AG | 2014-02-19 | — | — | CN | disclosed |
| EP-2624699-A1 | FUNGICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A THIAZOLYLPIPERIDINE DERIVATIVE | Bayer CropScience Aktiengesellschaft (DE) | 2013-08-14 | — | — | EP | disclosed |
| WO-2013014227-A1 | SEED DRESSING FOR CONTROLLING PHYTOPATHOGENIC FUNGI | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-31 | — | — | WO | disclosed |
| WO-2012045798-A1 | FUNGICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A THIAZOLYLPIPERIDINE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2012-04-12 | — | — | WO | disclosed |
| CN-102232067-A | Nicotinamide derivatives | CRC FOR BIOMEDICAL IMAGING DEV LTD | 2011-11-02 | — | — | CN | disclosed |
| US-7943643-B2 | Aryl substituted pyridines and the use thereof | PURDUE PHARMA L.P. (US) | 2011-05-17 | — | — | US | disclosed |
| US-20100048626-A1 | Aryl Substituted Pyridines and the Use Thereof | PURDUE PHARMA L.P. | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057505-A1 | BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY | F2RL1, PARP12, TFPI2 | PARP1 11/4885KDM4E 4542/4885ALDH1A1 3037/4885 |
| US-20100048626-A1 | Aryl Substituted Pyridines and the Use Thereof | CACNA1S, CACNA1E, CACNA1C | PARP1 1966/4885KDM4E 1567/4885ALDH1A1 76/4885 |
| US-11504439-B2 | Radioactive compound for diagnosis of malignant melanoma and use thereof | MITF, BRAF, MEN1 | PARP1 3553/4885KDM4E 767/4885ALDH1A1 1207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.