Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | AGER | Q15109 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | DHODH | Q02127 | 3/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM6A | O15550 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30863406 | 1.00 | KDM4E (0.63) | KDM4ETDP1ALDH1A1L3MBTL1ALOX15 | |
| Nitrous Acid SCHEMBL27941916 | 0.92 | ALDH1A1 (0.58) | KDM4ETDP1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL12469484 | 0.81 | PARP1 (0.56) | KDM4ETDP1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL16414377 | 0.81 | KDM4E (0.45) | KDM4ETDP1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL1807370 | 0.80 | TDP1 (0.55) | KDM4ETDP1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL270419 | 0.77 | KDM4E (1.00) | KDM4ETDP1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL15850545 | 0.77 | KDM4E (0.77) | KDM4ETDP1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL21048718 | 0.76 | PTPN1 (0.44) | KDM4ETDP1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL22258205 | 0.76 | POLB (0.69) | TDP1ALDH1A1L3MBTL1CYP3A4MAPT | |
| SCHEMBL6032802 | 0.76 | TSHR (0.59) | KDM4EALDH1A1L3MBTL1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521249-B | 2- [4- (1-Oxo alkyl) phenoxy ] -3-picolinic acid, preparation method and application thereof | 沈阳兴齐眼药股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| US-20240343738-A1 | Method for preparing pranoprofen and composition comprising pranoprofen and impurity | SHENYANG XINGQI PHARMACEUTICAL CO., LTD. (CN) | 2024-10-17 | — | — | US | claimed |
| EP-4361155-A1 | METHOD FOR PREPARING PRANOPROFEN AND COMPOSITION CONTAINING PRANOPROFEN AND IMPURITY | Shenyang Xingqi Pharmaceutical Co., Ltd. (CN) | 2024-05-01 | — | — | EP | claimed |
| CN-114685365-B | Synthesis method of diflufenican | 青岛润农化工有限公司 | 2023-06-30 | — | — | CN | claimed |
| WO-2022267945-A1 | METHOD FOR PREPARING PRANOPROFEN AND COMPOSITION CONTAINING PRANOPROFEN AND IMPURITY | 沈阳兴齐眼药股份有限公司 | 2022-12-29 | — | — | WO | claimed |
| CN-115521249-A | 2- [4- (1-oxoalkyl) phenoxy ] -3-picolinic acid, preparation method and application thereof | 沈阳兴齐眼药股份有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-114685365-A | Synthetic method of diflufenican | 青岛润农化工有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-115521249-B | 2- [4- (1-Oxo alkyl) phenoxy ] -3-picolinic acid, preparation method and application thereof | 沈阳兴齐眼药股份有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-115521250-B | 2- (10-Hydroxy-9-oxa-1-aza-6-yl) propionate compound, and preparation method and application thereof | 沈阳兴齐眼药股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-115521251-B | Pranoprofen intermediate compound, preparation method and application thereof | 沈阳兴齐眼药股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
| US-20240343738-A1 | Method for preparing pranoprofen and composition comprising pranoprofen and impurity | SHENYANG XINGQI PHARMACEUTICAL CO., LTD. (CN) | 2024-10-17 | — | — | US | disclosed |
| EP-4361155-A1 | METHOD FOR PREPARING PRANOPROFEN AND COMPOSITION CONTAINING PRANOPROFEN AND IMPURITY | Shenyang Xingqi Pharmaceutical Co., Ltd. (CN) | 2024-05-01 | — | — | EP | disclosed |
| CN-115521320-B | Method for preparing pranoprofen | 沈阳兴齐眼药股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-2647620-A1 | STABLE SYNTHETIC INTERMEDIATE AND METHOD FOR MANUFACTURING SAME | Kyorin Pharmaceutical Co., Ltd. (JP) | 2013-10-09 | — | — | EP | disclosed |
| WO-2010147776-A1 | SUBSTITUTED -1,3,8-TRIAZASPIRO[4.5]DECANE-2,4-DIONES | MERCK SHARP & DOHME CORP. (US) | 2010-12-23 | — | — | WO | disclosed |
| EP-2240178-A1 | PROLYL HYDROXYLASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009086044-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITH KLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
| EP-1086080-B1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2004-08-25 | — | — | EP | disclosed |
| EP-1086080-A1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065872-A1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343738-A1 | Method for preparing pranoprofen and composition comprising pranoprofen and impurity | CYP3A5, CYP3A43, CYP4A11 | KDM4E 3123/4885TDP1 991/4885ALDH1A1 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.