Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | SMO | Q99835 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469317 | 0.94 | NPSR1 (0.61) | NPSR1ALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL12469234 | 0.84 | ALDH1A1 (0.61) | NPSR1ALDH1A1MAPTSIGMAR1SLC6A2 | |
| SCHEMBL12469411 | 0.81 | SLC6A2 (0.52) | NPSR1ALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL12469002 | 0.78 | ALDH1A1 (0.58) | NPSR1ALDH1A1TSHRSIGMAR1SLC6A2 | |
| SCHEMBL12469049 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTTSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL12468893 | 0.77 | SIGMAR1 (0.53) | ALDH1A1MAPTTSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL12469487 | 0.76 | SLC6A2 (0.52) | ALDH1A1MAPTTSHRSMN1; SMN2SLC6A2 | |
| SCHEMBL10573394 | 0.76 | SIGMAR1 (0.49) | NPSR1ALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL7680682 | 0.76 | SIGMAR1 (0.53) | ALDH1A1MAPTTSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL12469349 | 0.76 | SLC6A2 (0.56) | NPSR1ALDH1A1MAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130289047-A1 | HETEROARYLTHIO DERIVATIVES AND ANALOGUES | EPIOMED THERAPEUTICS, INC. (US) | 2013-10-31 | — | — | US | disclosed |
| WO-2012051601-A2 | HETEROARYLTHIO COMPOUNDS | EPIOMED THERAPEUTICS, INC. (US) | 2012-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130289047-A1 | HETEROARYLTHIO DERIVATIVES AND ANALOGUES | NLN, HTT, ABAT | NPSR1 1962/4885ALDH1A1 2297/4885MAPT 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.