Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28832707 | 0.82 | CSNK1D (0.39) | IKBKBCHUK | |
| SCHEMBL1842323 | 0.65 | NPC1 (0.52) | NPC1HPGD | |
| SCHEMBL15266295 | 0.64 | KMT2A (0.34) | — | |
| Hydrochloric Acid SCHEMBL1844041 | 0.64 | NPC1 (0.51) | NPC1HPGD | |
| SCHEMBL7534511 | 0.64 | ALDH1A1 (0.51) | — | |
| SCHEMBL1292197 | 0.62 | NCOA1 (0.36) | — | |
| SCHEMBL7539138 | 0.62 | SMN1; SMN2 (0.48) | NPC1HPGD | |
| SCHEMBL7242715 | 0.61 | ALDH1A1 (0.40) | HPGD | |
| SCHEMBL7536844 | 0.61 | SIRT1 (0.38) | NPC1HPGD | |
| SCHEMBL1292458 | 0.61 | MAOB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2625178-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | Biota Europe Ltd (GB) | 2013-08-14 | — | — | EP | disclosed |
| WO-2012045124-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | BIOTA EUROPE LTD (GB) | 2012-04-12 | — | — | WO | disclosed |