Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240096 | 0.93 | MAPT (0.43) | MAPTKDM4EKMT2ASMN1; SMN2POLB | |
| SCHEMBL236762 | 0.85 | KDM4E (0.35) | MAPTKDM4EKMT2ASMN1; SMN2POLB | |
| SCHEMBL12547367 | 0.79 | ALDH1A1 (0.49) | MAPTKMT2ASMN1; SMN2MEN1NPSR1 | |
| SCHEMBL6211391 | 0.78 | ALDH1A1 (0.40) | MAPTKDM4EKMT2ASMN1; SMN2POLB | |
| SCHEMBL30890308 | 0.77 | HTT (0.53) | MAPTKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31640059 | 0.77 | HTT (0.53) | MAPTKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4705323 | 0.76 | ALDH1A1 (0.41) | MAPTKMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4703887 | 0.75 | ALDH1A1 (0.40) | MAPTKDM4EKMT2ASMN1; SMN2POLB | |
| SCHEMBL5281743 | 0.74 | ALDH1A1 (0.38) | MAPTKMT2APOLBALDH1A1LMNA | |
| SCHEMBL6209802 | 0.74 | ALDH1A1 (0.39) | MAPTKMT2ASMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678334-A1 | ANTI-VIRAL COMPOUNDS | Abbvie Inc. (US) | 2014-01-01 | — | — | EP | disclosed |
| EP-2627651-A1 | ANTI-VIRAL COMPOUNDS | Abbvie Inc. (US) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012116257-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. (US) | 2012-08-30 | — | — | WO | disclosed |
| WO-2012051361-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-04-19 | — | — | WO | disclosed |