Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489081 | 0.87 | APEX1 (0.53) | PPARGFFAR1PPARDPPARAALOX5 | |
| SCHEMBL39941 | 0.87 | APEX1 (0.53) | PPARGFFAR1PPARDPPARAALOX5 | |
| SCHEMBL9301856 | 0.87 | APEX1 (0.53) | PPARGFFAR1PPARDPPARAALOX5 | |
| SCHEMBL2490383 | 0.86 | ALOX5 (0.54) | PPARGALOX5THRBMAPTNPC1 | |
| SCHEMBL28162326 | 0.84 | MAPT (0.41) | PPARGFFAR1PPARDPPARATHRB | |
| SCHEMBL6367852 | 0.84 | ALOX5 (0.58) | PPARGALOX5THRBMAPTNPC1 | |
| SCHEMBL9010520 | 0.84 | LMNA (0.46) | PPARGFFAR1PPARDPPARAALOX5 | |
| SCHEMBL8153624 | 0.81 | NPC1 (0.59) | PPARGFFAR1PPARDPPARATHRB | |
| SCHEMBL489474 | 0.81 | ALOX5 (0.48) | PPARGALOX5THRBMAPTNPC1 | |
| SCHEMBL8153618 | 0.81 | NPC1 (0.59) | PPARGFFAR1PPARDPPARATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012049453-A2 | COMPOSITIONS FOR TOPICAL APPLICATIONS | VECTUM PHARMA S.L. (ES) | 2012-04-19 | — | — | WO | disclosed |