SCHEMBL489474

SCHEMBL489474

CCCC(=Cc1ccc(OC)cc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.48
MAPT P10636 3/20 0.48
THRB P10828 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
ATM Q13315 1/20 0.47
GSK3B P49841 2/20 0.46
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
AKR1C3 P42330 1/20 0.46
F3 P13726 1/20 0.45
TRPM8 Q7Z2W7 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44
APEX1 P27695 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6367852 0.91 ALOX5 (0.58) ALOX5MAPTTHRBNPC1RAB9A
SCHEMBL2490383 0.89 ALOX5 (0.54) ALOX5MAPTTHRBNPC1RAB9A
SCHEMBL9301856 0.88 APEX1 (0.53) ALOX5MAPTTHRBNPC1RAB9A
Butyric Acid SCHEMBL7821661 0.88 RAB9A (0.50) ALOX5MAPTTHRBNPC1RAB9A
SCHEMBL39941 0.88 APEX1 (0.53) ALOX5MAPTTHRBNPC1RAB9A
SCHEMBL2489081 0.88 APEX1 (0.53) ALOX5MAPTTHRBNPC1RAB9A
Butyric Acid SCHEMBL7821663 0.88 RAB9A (0.50) ALOX5MAPTTHRBNPC1RAB9A
SCHEMBL3147453 0.87 GSK3B (0.46) MAPTTHRBNPC1RAB9AATM
SCHEMBL3147460 0.87 GSK3B (0.46) MAPTTHRBNPC1RAB9AATM
SCHEMBL8153624 0.87 NPC1 (0.59) MAPTTHRBNPC1RAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2379625-B1 UV AND LIGHT PROTECTIVE FILM HUHTAMAKI FORCHHEIM (DE) 2013-02-20 EP claimed
CN-102356121-A Uv and light protective film HUHTAMAKI FORCHHEIM 2012-02-15 CN claimed
EP-2379625-A1 UV AND LIGHT PROTECTIVE FILM Huhtamaki Forchheim Zweigniederlassung der Huhtamaki Deutschland GmbH & Co. KG (DE) 2011-10-26 EP claimed
WO-2010075946-A1 UV AND LIGHT PROTECTIVE FILM HUHTAMAKI FORCHHEIM, ZWEIGNIEDERLASSUNG DER HUHTAMAKI DEUTSCHLAND GMBH & CO. KG (DE) 2010-07-08 WO claimed
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION ISDIN S.A. (ES) 2010-02-25 US claimed
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 WO claimed
WO-2026106274-A1 HAIR COSMETIC COMPOSITION HAVING EXCELLENT PHOTOPROTECTIVE EFFICACY 한국콜마주식회사 2026-05-21 WO disclosed
US-12589062-B2 Powdery solid cosmetic preparation SHISEIDO COMPANY, LTD. (JP) 2026-03-31 US disclosed
US-20260076892-A1 GEL COMPOSITION AND OIL-IN-WATER COMPOSITION SHISEIDO COMPANY, LTD. (JP) 2026-03-19 US disclosed
US-20260078211-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE DOW TORAY CO LTD (JP) 2026-03-19 US disclosed
EP-4626941-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE Dow Toray Co., Ltd. (JP) 2025-10-08 EP disclosed
EP-4628568-A1 GEL CLEANING AGENT AND METHOD FOR PRODUCING THE SAME Shiseido Honeycake Industries Co., Ltd. (JP) 2025-10-08 EP disclosed
EP-4620453-A1 AQUEOUS DISPERSION OF SURFACE-HYDROPHOBIZED INORGANIC POWDER AND COSMETIC PREPARATION CONTAINING SAME Nikko Chemicals Co., Ltd. (JP) 2025-09-24 EP disclosed
WO-2001091715-A2 TOPICAL AGENT FOR DERMATOLOGICAL USE CONTAINING 4-HYDROXYPHENYL-ALPHA-D-GLUCOPYRANOSIDE PENTAPHARM LTD. (CH) 2001-12-06 WO disclosed
EP-1153602-A1 SKIN PREPARATIONS FOR EXTERNAL USE SHISEIDO COMPANY LIMITED (JP) 2001-11-14 EP disclosed
WO-2001072935-A2 UV-ABSORBING MIXTURE WITH TEXTILE FIBRE AFFINITY BASF AKTIENGESELLSCHAFT (DE) 2001-10-04 WO disclosed
US-6150425-A COMPRISING AN OUTER PHASE OIL AND OIL IN WATER EMULSION IN THE INNER PHASE WHICH CONTAINING WATER, AN OIL BASED INGREDIENT, A SURFACTANT AND AN AMPHIPHILIC SUBSTANCE; PREPARED BY A HIGH PRESSURE OR ULTRASONIC EMULSIFICATION SHISEIDO COMPANY, LTD. (JP) 2000-11-21 US disclosed
WO-2000057840-A2 DERMATOLOGICAL TOPICAL COMPOSITION PENTAPHARM AG (CH) 2000-10-05 WO disclosed
EP-1002515-A1 SKIN COMPOSITIONS FOR EXTERNAL USE SHISEIDO COMPANY LIMITED (JP) 2000-05-24 EP disclosed
EP-0970741-A1 O/W/O TYPE MULTIPHASE EMULSION SHISEIDO COMPANY LIMITED (JP) 2000-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260076892-A1 GEL COMPOSITION AND OIL-IN-WATER COMPOSITION SGMS1, SGMS2, CETP ALOX5 503/4885MAPT 2209/4885THRB 3255/4885
US-20260078211-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE FOXM1, FOXK1, TAF1L ALOX5 513/4885MAPT 2752/4885THRB 4408/4885
US-12589062-B2 Powdery solid cosmetic preparation TMEM63A, CUTA, VCL ALOX5 2966/4885MAPT 2757/4885THRB 690/4885
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION UGT2B17, TACR2, UGT1A1 ALOX5 1030/4885MAPT 922/4885THRB 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.