Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22114693 | 0.87 | TRPA1 (0.38) | ABL1BRD4PAX8POLBTP53 | |
| SCHEMBL22115069 | 0.85 | CISD2 (0.36) | CISD2MEN1KMT2ACYP1A2POLB | |
| SCHEMBL22439649 | 0.84 | PDK2 (0.46) | ABL1BRD4PAX8MAPTIRAK4 | |
| SCHEMBL30116140 | 0.84 | AAK1 (0.40) | ABL1BRD4PAX8POLBSMN1; SMN2 | |
| SCHEMBL18157855 | 0.84 | ABL1 (0.39) | ABL1BRD4MEN1KMT2APAX8 | |
| SCHEMBL20671184 | 0.84 | AAK1 (0.40) | ABL1BRD4PAX8POLBSMN1; SMN2 | |
| SCHEMBL30369795 | 0.84 | ABL1 (0.39) | ABL1BRD4MEN1KMT2APAX8 | |
| SCHEMBL25736560 | 0.82 | ABL1 (0.36) | ABL1BRD4MEN1KMT2APAX8 | |
| SCHEMBL18160482 | 0.81 | ABL1 (0.36) | ABL1BRD4PAX8MAPTIRAK4 | |
| SCHEMBL27525594 | 0.81 | ALDH1A1 (0.44) | ABL1MEN1KMT2ACYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020119606-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2020-06-18 | — | — | WO | disclosed |