Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17287226 | 0.83 | ALDH1A1 (0.54) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL500715 | 0.82 | LMNA (0.56) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL22360955 | 0.80 | LMNA (0.54) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL29446652 | 0.79 | IDO1 (0.56) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL23162526 | 0.79 | IDO1 (0.56) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL26352410 | 0.79 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| Water SCHEMBL28964119 | 0.78 | LMNA (0.52) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| Water SCHEMBL28150223 | 0.78 | LMNA (0.52) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL19497384 | 0.76 | RAB9A (0.53) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL15862445 | 0.74 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2787053-B1 | Polymeric materials | MERCK PATENT GMBH (DE) | 2018-11-21 | — | — | EP | disclosed |
| EP-2627732-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| CN-103228759-B | Material for organic electroluminescent device | 弗朗霍夫应用科学研究促进协会 | 2016-10-26 | — | — | CN | disclosed |
| EP-2787053-A1 | Polymeric materials | Merck Patent GmbH (DE) | 2014-10-08 | — | — | EP | disclosed |
| US-8786181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| EP-2627732-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | Merck Patent GmbH (DE) | 2013-08-21 | — | — | EP | disclosed |
| US-20130207095-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Fraunhofer-Gesellschaft Forderung E.V. (DE) | 2013-08-15 | — | — | US | disclosed |
| WO-2012048900-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. . (DE) | 2012-04-19 | — | — | WO | disclosed |