SCHEMBL124704

SCHEMBL124704

COCCOCCOC[C]=O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29256269 1.00 CA2 (0.38) CA2MEN1KMT2A
SCHEMBL1758519 0.97
SCHEMBL2780260 0.86 MEN1 (0.32) MEN1KMT2A
SCHEMBL2387118 0.82
SCHEMBL29256263 0.79 ALDH1A1 (0.41) MEN1KMT2A
SCHEMBL785513 0.79 CA2 (0.38) CA2
SCHEMBL7291462 0.79 CA2 (0.38) CA2
SCHEMBL2385202 0.79
SCHEMBL20513010 0.79 ALDH1A1 (0.41) MEN1KMT2A
SCHEMBL23647292 0.76 CA2 (0.44) CA2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100291191-A1 TUNABLE SUSTAINED RELEASE OF A SPARINGLY SOLUBLE HYDROPHOBIC THERAPEUTIC AGENT FROM A HYDROGEL MATRIX THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2010-11-18 US claimed
US-20100285113-A1 ENHANCED STABILITY OF INVERSE THERMAL GELLING COMPOSITE HYDROGELS THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2010-11-11 US claimed
US-7666866-B2 Antithrombotic diamides ELI LILLY AND COMPANY (US) 2010-02-23 US claimed
EP-1819693-B1 ANTITHROMBOTIC DIAMIDES LILLY CO ELI (US) 2009-08-26 EP claimed
US-20090062271-A1 Antithrombotic Diamides ELI LILLY AND COMPANY (US) 2009-03-05 US claimed
EP-1819693-A1 ANTITHROMBOTIC DIAMIDES ELI LILLY AND COMPANY (US) 2007-08-22 EP claimed
WO-2006057868-A1 ANTITHROMBOTIC DIAMIDES ELI LILLY AND COMPANY (US) 2006-06-01 WO claimed
EP-1189891-A1 TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF LION Bioscience AG (DE) 2002-03-27 EP claimed
US-6362342-B1 BIOSYNTHESIS; DRUG LIBRARIES LION BIOSCIENCE AG (DE) 2002-03-26 US claimed
WO-2001000594-A1 TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-01-04 WO claimed
WO-1998040078-A1 THERAPEUTIC AUGMENTATION OF OXYALKYLENE DIESTERS AND BUTYRIC ACID DERIVATIVES BEACON LABORATORIES, INC. (US) 1998-09-17 WO claimed
EP-0703921-A1 GRAFTED CROSS-LINKED POLYOLEFIN SUBSTRATES FOR PEPTIDE SYNTHESIS AND ASSAYS FORSKNINGSCENTER RISO (DK) 1996-04-03 EP claimed
WO-1995000533-A1 GRAFTED CROSS-LINKED POLYOLEFIN SUBSTRATES FOR PEPTIDE SYNTHESIS AND ASSAYS Forskningscenter Risø (DK) 1995-01-05 WO claimed
EP-0344990-B1 Mitomycin derivatives and intermediates therefor KYOWA HAKKO KOGYO KK (JP) 1993-12-15 EP claimed
EP-0344990-A1 Mitomycin derivatives and intermediates therefor KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1989-12-06 EP claimed
EP-0144290-A2 Substituted ethylenediamine derivatives CIBA-GEIGY AG (CH) 1985-06-12 EP claimed
US-20230312700-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A TNF INHIBITOR GLAS USA LLC 2023-10-05 US disclosed
EP-4232146-A1 METHODS OF TREATING AND PREDICTING NON-RESPONSE TO ANTI-TNF TREATMENT IN SUBJECTS WITH GASTROINTESTINAL TRACT DISEASES Biora Therapeutics, Inc. (US) 2023-08-30 EP disclosed
EP-0337334-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1989-10-18 EP disclosed
EP-0144290-A2 Substituted ethylenediamine derivatives CIBA-GEIGY AG (CH) 1985-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062271-A1 Antithrombotic Diamides TFPI, SERPINC1, TFPI2 CA2 960/4885MEN1 1118/4885KMT2A 4224/4885
US-20230312700-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A TNF INHIBITOR TNF, TNFRSF1A, FABP2 CA2 3630/4885MEN1 1615/4885KMT2A 4751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.