Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18590739 | 0.98 | SOS1 (0.46) | L3MBTL1EGFRGAAMAPTTDP1 | |
| SCHEMBL13456177 | 0.82 | SOS1 (0.73) | SOS1 | |
| SCHEMBL18591949 | 0.82 | MAPT (0.45) | GAAMAPTTDP1HPGDNPC1 | |
| SCHEMBL18590729 | 0.79 | MEN1 (0.42) | EGFRGAAMAPTRAPGEF4NPC1 | |
| SCHEMBL3371377 | 0.79 | MAPT (0.60) | L3MBTL1EGFRGAAMAPTTDP1 | |
| SCHEMBL5667044 | 0.78 | RAPGEF4 (0.63) | L3MBTL1EGFRGAAMAPTTDP1 | |
| SCHEMBL30146931 | 0.78 | RAPGEF4 (0.63) | L3MBTL1EGFRGAAMAPTTDP1 | |
| SCHEMBL27786542 | 0.78 | MAP2K2 (0.44) | RAPGEF4SOS1MAP2K2MAP2K1MAPK1 | |
| SCHEMBL22563167 | 0.78 | PGR (0.42) | RAPGEF4MAP2K2MAP2K1DHODHMEN1 | |
| SCHEMBL5028501 | 0.77 | RAPGEF4 (0.61) | L3MBTL1EGFRGAAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017034023-A1 | COMPLEX AND OPTICAL ELEMENT | 国立大学法人京都大学 | 2017-03-02 | — | — | WO | disclosed |
| US-20130193382-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2013-08-01 | — | — | US | disclosed |
| WO-2012048780-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-04-19 | — | — | WO | disclosed |