Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8166064 | 0.92 | G6PC1 (0.49) | G6PC1MAOATAAR1ADORA2ANR4A1 | |
| SCHEMBL4250239 | 0.85 | NR4A1 (0.59) | G6PC1MAOAADORA2ANR4A1USP2 | |
| SCHEMBL4250235 | 0.85 | NR4A1 (0.59) | G6PC1MAOAADORA2ANR4A1USP2 | |
| SCHEMBL13197243 | 0.82 | G6PC1 (0.58) | G6PC1MAOAADORA2ANR4A1USP2 | |
| SCHEMBL34460869 | 0.82 | G6PC1 (0.58) | G6PC1MAOAADORA2ANR4A1USP2 | |
| SCHEMBL8719353 | 0.82 | NR4A1 (0.55) | G6PC1MAOAADORA2ANR4A1USP2 | |
| SCHEMBL12714965 | 0.82 | NR4A1 (0.55) | G6PC1MAOAADORA2ANR4A1USP2 | |
| SCHEMBL4254675 | 0.81 | MAOA (0.53) | G6PC1MAOAADORA2ANR4A1USP2 | |
| SCHEMBL4255814 | 0.81 | MAOA (0.53) | G6PC1MAOAADORA2ANR4A1USP2 | |
| SCHEMBL10308820 | 0.79 | NR4A1 (0.52) | G6PC1MAOANR4A1USP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012109343-A2 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-08-16 | — | — | WO | disclosed |