Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16704594 | 0.90 | GABRA1 (0.38) | HTTLMNAMAPTSMN1; SMN2PARP1 | |
| SCHEMBL12685773 | 0.90 | HTT (0.33) | HTTLMNAMAPTHPGDMAPK1 | |
| SCHEMBL16704596 | 0.87 | GABRA1 (0.38) | HTTMAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL16704600 | 0.85 | CYP1A2 (0.33) | HTTLMNAMAPTHPGDMAPK1 | |
| SCHEMBL12685781 | 0.84 | KMT2A (0.39) | HTTLMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL16704586 | 0.84 | GABRA1 (0.38) | HTTLMNAMAPTSMN1; SMN2PARP1 | |
| SCHEMBL16704595 | 0.84 | GABRA1 (0.38) | HTTLMNAMAPTSMN1; SMN2PARP1 | |
| SCHEMBL22717620 | 0.83 | ENPP1 (0.36) | HTTMAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL3357702 | 0.82 | BACE1 (0.38) | HTTLMNAMAPTHPGDMAPK1 | |
| SCHEMBL12470668 | 0.81 | ALDH1A1 (0.45) | MAPTHPGDMAPK1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673249-B1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2019-04-03 | — | — | EP | disclosed |
| EP-2673249-B1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2019-04-03 | — | — | EP | disclosed |
| US-9029425-B2 | Substituted dibenzo[FG,OP]tetracenes and formulations or electronic devices containing the same | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-9029425-B2 | Substituted dibenzo[FG,OP]tetracenes and formulations or electronic devices containing the same | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-9029425-B2 | Substituted dibenzo[FG,OP]tetracenes and formulations or electronic devices containing the same | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| EP-2673249-A1 | SUBSTITUTED DIBENZONAPHTHACENE | Merck Patent GmbH (DE) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107163-A1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |
| WO-2012107163-A1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |