Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 3/20 | 0.38 |
| ▸ | CCND1 | P24385 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12685738 | 0.90 | ALDH1A1 (0.37) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL16704599 | 0.90 | MAOA (0.39) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL16704591 | 0.87 | MAOA (0.39) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL2852878 | 0.86 | CYP1A2 (0.46) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL22717620 | 0.84 | ENPP1 (0.36) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL3357702 | 0.83 | BACE1 (0.38) | ALDH1A1HPGDHSD17B10ACHEKDM4E | |
| SCHEMBL16859288 | 0.82 | HPGD (0.34) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL16859286 | 0.82 | BACE1 (0.37) | ALDH1A1HPGDACHEKDM4EMEN1 | |
| SCHEMBL12470528 | 0.81 | HTT (0.41) | HPGDHSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL4886590 | 0.80 | MEN1 (0.45) | ALDH1A1HPGDHSD17B10CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673249-B1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2019-04-03 | — | — | EP | disclosed |
| US-9029425-B2 | Substituted dibenzo[FG,OP]tetracenes and formulations or electronic devices containing the same | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| EP-2673249-A1 | SUBSTITUTED DIBENZONAPHTHACENE | Merck Patent GmbH (DE) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107163-A1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |