Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18236653 | 0.79 | CHRM2 (0.53) | MAPTMEN1KMT2ATDP1CHRM2 | |
| SCHEMBL5084056 | 0.76 | MAPT (0.48) | MAPTMEN1KMT2ATDP1GAA | |
| SCHEMBL7615058 | 0.74 | CHRM2 (0.51) | MAPTMEN1KMT2ATDP1CHRM2 | |
| SCHEMBL11206002 | 0.72 | MAPT (0.50) | MAPTMEN1KMT2ATDP1CHRM2 | |
| SCHEMBL6327499 | 0.71 | MAPT (0.56) | MAPTMEN1KMT2ATDP1CHRM2 | |
| SCHEMBL28319292 | 0.71 | ADRB2 (0.57) | MAPTMEN1KMT2ATDP1CHRM2 | |
| SCHEMBL10632588 | 0.70 | CHRM2 (0.59) | MAPTMEN1KMT2ATDP1CHRM2 | |
| SCHEMBL16340151 | 0.70 | MAPT (0.51) | MAPTMEN1KMT2ATDP1CHRM2 | |
| SCHEMBL28587054 | 0.70 | ALDH1A1 (0.49) | MAPTMEN1KMT2ATDP1CHRM2 | |
| SCHEMBL10245032 | 0.69 | CA1 (0.42) | MEN1KMT2AL3MBTL1LPAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012109343-A2 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-08-16 | — | — | WO | disclosed |