Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 14/20 | 0.70 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MMP14 | P50281 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468132 | 0.99 | INSR (0.72) | INSRAPPMAPTKMT2ATHRB | |
| SCHEMBL17322556 | 0.87 | INSR (0.75) | INSRAPPMAPTKMT2ATHRB | |
| SCHEMBL12880678 | 0.86 | INSR (0.63) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL38659057 | 0.84 | INSR (0.79) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL5679445 | 0.84 | INSR (0.97) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL29757617 | 0.84 | INSR (0.97) | INSRAPPMAPTKMT2ATHRB | |
| SCHEMBL13005219 | 0.84 | INSR (0.64) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL7028400 | 0.84 | INSR (0.97) | INSRAPPMAPTKMT2ATHRB | |
| SCHEMBL16263357 | 0.84 | INSR (0.67) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL7104931 | 0.83 | INSR (0.77) | INSRAPPMAPTKMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673642-A1 | PROCESS FOR DETECTING CELLS FROM A SAMPLE | FZMB GmbH Forschungszentrum für Medizintechnik und Biotechnologie (DE) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107559-A1 | PROCESS FOR DETECTING CELLS FROM A SAMPLE | FZMB GMBH FORSCHUNGSZENTRUM FÜR MEDIZINTECHNIK UND BIOTECHNOLOGIE (DE) | 2012-08-16 | — | — | WO | disclosed |