Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 15/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17322556 | 0.88 | INSR (0.75) | INSRAPPMAPTKMT2ATHRB | |
| SCHEMBL34468132 | 0.85 | INSR (0.72) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL12470899 | 0.84 | INSR (0.70) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL38659057 | 0.82 | INSR (0.79) | INSRAPPMAPTKMT2ATHRB | |
| SCHEMBL9580682 | 0.81 | INSR (1.00) | INSRAPPMAPTKMT2ATHRB | |
| SCHEMBL9580683 | 0.81 | INSR (1.00) | INSRAPPMAPTKMT2ATHRB | |
| Iodide SCHEMBL7028400 | 0.80 | INSR (0.97) | INSRAPPMAPTKMT2ATHRB | |
| SCHEMBL13005219 | 0.80 | INSR (0.64) | INSRAPPMAPTKMT2ATHRB | |
| Bromide SCHEMBL22598035 | 0.80 | INSR (0.97) | INSRAPPMAPTKMT2ATHRB | |
| Bromide SCHEMBL22598036 | 0.80 | INSR (0.97) | INSRAPPMAPTKMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160299078-A1 | Specific Detection and Quantification of Cardiolipin and Isolated Mitochondria by Positively Charged AIE Fluorogens and Method of Manufacturing Thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-10-13 | — | — | US | disclosed |
| US-9279806-B2 | Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-03-08 | — | — | US | disclosed |
| US-9109155-B2 | Heterocycle-functionalized luminogens exhibiting aggregation-induced emission | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-08-18 | — | — | US | disclosed |
| US-9109155-B2 | Heterocycle-functionalized luminogens exhibiting aggregation-induced emission | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-08-18 | — | — | US | disclosed |
| WO-2015081860-A1 | SPECIFIC DETECTION AND QUANTIFICATION OF CARDIOLIPIN AND ISOLATED MITOCHONDRIA BY POSITIVELY CHARGED AIE FLUOROGENS AND METHOD OF MANUFACTURING THEREOF | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-06-11 | — | — | WO | disclosed |
| US-20150031607-A1 | WATER-SOLUBLE AIE LUMINOGENS FOR MONITORING AND RETARDATION OF FIBRILLATION OF AMYLOID PROTEINS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-01-29 | — | — | US | disclosed |
| US-20140348753-A1 | HETEROCYCLE-FUNCTIONALIZED LUMINOGENS EXHIBITING AGGREGATION-INDUCED EMISSION | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2014-11-27 | — | — | US | disclosed |
| US-20140348753-A1 | HETEROCYCLE-FUNCTIONALIZED LUMINOGENS EXHIBITING AGGREGATION-INDUCED EMISSION | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140348753-A1 | HETEROCYCLE-FUNCTIONALIZED LUMINOGENS EXHIBITING AGGREGATION-INDUCED EMISSION | HSPE1, HAGH, LETM1 | INSR 1001/4885APP 1191/4885MAPT 2779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.